Overcoming steroid resistance in T cell acute lymphoblastic leukemia [PDF]
, 2016 In a Perspective, Pieter Van Vlierberghe and Steven Goossens discuss Meijerink and colleagues' findings on steroid resistance in pediatric T cell acute lymphoblastic ...
Goossens, Steven +1 more
core +3 more sources
Green Synthesis of Bismuth Oxide Nanoparticle by cell-free extract of Spirulina Platensis and evaluation of its performance on expression of apoptosis regulator genes in MCF-7 breast cancer cell line [PDF]
Journal of Epigenetics, 2022 Background and Aim: Bismuth and its related compounds such as bismuth oxide nanoparticles (Bi2O3 NPs) are widely used in the medical field of science for drug delivery, cancer therapy, bio imaging, and fighting against pathogenic microorganisms.
Maedeh Khorami +2 more
doaj +1 more source
TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells [PDF]
, 2013 Using a screening strategy, we identified the tetratricopeptide repeat (TPR) motif protein, Tetratricopeptide repeat domain 5 (TTC5, also known as stress responsive activator of p300 or Strap) as required for the survival of human acute myeloid leukemia (
Huang, X. +4 more
core +1 more source
Diffuse large B-cell lymphoma with concomitant c-MYC and BCL6 gene rearrangements with primary skin involvement: A case report and a review of literature [PDF]
Терапевтический архив, 2017 Double-hit lymphoma (DHL) is a rare aggressive B-cell lymphoma with concomitant c-MYC, BCL2 or BCL6 gene rearrangements, which is characterized by the high frequency of extranodal lesions and by resistance to chemotherapy.
N G Gabeeva +9 more
doaj +1 more source
JMJD3 promotes survival of diffuse large B-cell lymphoma subtypes via distinct mechanisms. [PDF]
, 2016 JMJD3 (Jumonji domain containing-3), a histone H3 Lys27 (H3K27) demethylase, has been reported to be involved in the antigen-driven differentiation of germinal center B-cells.
Bai, Nan +10 more
core +1 more source
BAG1 (BCL2-associated athanogene) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on BAG1 (BCL2-associated athanogene), with data on DNA, on the protein encoded, and where the gene is implicated.
Southern, SL, Skeen, V, Williams, AC
openaire +3 more sources
Targeting BCL-2 regulated apoptosis in cancer [PDF]
, 2018 The ability of a cell to undergo mitochondrial apoptosis is governed by pro- and anti-apoptotic members of the BCL-2 protein family. The equilibrium of pro- versus anti-apoptotic BCL-2 proteins ensures appropriate regulation of programmed cell death ...
Campbell, Kirsteen J. +1 more
core +1 more source
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on BCL2L15 (BCL2-like 15), with data on DNA, on the protein encoded, and where the gene is implicated.
Pavlou, MAS, Kontos, CK
openaire +3 more sources
Tissue Inhibitor of Metalloproteinase–3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells [PDF]
, 2018 Over expression of Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) in vascular smooth muscle cells (VSMCs) induces apoptosis and reduces neointima formation occurring after saphenous vein interposition grafting or coronary stenting.
Baker, Andrew H. +5 more
core +4 more sources
Hepatology, EarlyView., 2022 CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source