Results 61 to 70 of about 146,281 (306)
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Genomic studies indicate a novel combination therapy for follicular lymphoma
Molecular & Cellular Oncology, 2021 Follicular lymphoma (FL) is an incurable form of B-cell lymphoma. Genomic alterations that inactivate RB signaling are surprisingly common in indolent FL. We show that FLs that are positive for phosphorylated RB respond to dual CDK4/BCL2 inhibition.
Elisa Oricchio, Hans-Guido Wendel
doaj +1 more source
Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing [PDF]
, 2011 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Aberrant DNA methylation plays a pivotal
Beltran, L +14 more
core +2 more sources
BCL2 genotypes and prostate cancer survival [PDF]
Strahlentherapie und Onkologie, 2017 The antiapoptotic B‑cell lymphoma 2 (BCL2) gene is a key player in cancer development and progression. A functional single-nucleotide polymorphism (c.-938C>A, rs2279115) in the inhibitory P2 BCL2 gene promoter has been associated with clinical outcomes in various types of cancer. Aim of the present study was to analyze the role of BCL2-938C>A genotypes
Wilfried Renner +4 more
openaire +2 more sources
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
مجله انفورماتیک سلامت و زیست پزشکی, 2014 Introduction: New diagnostic methods like immunohistochemistry staining in skin cancer can help the physicians to have more accurate diagnosis. The purpose of this study was to compare a method based on decision tree for differential diagnosis of two ...
Afshin Sarafi Nejad +3 more
doaj
Caspase-independent programmed cell death triggers Ca2PO4 deposition in an in vitro model of nephrocalcinosis [PDF]
, 2018 We provide evidence of caspase-independent cell death triggering the calcification process in GDNF-silenced HK-2 ...
Anglani F. +8 more
core +1 more source
BAG1 (BCL2-associated athanogene) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on BAG1 (BCL2-associated athanogene), with data on DNA, on the protein encoded, and where the gene is implicated.
Southern, SL, Skeen, V, Williams, AC
openaire +2 more sources
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Indian Journal of Pathology and MicrobiologyBackground: Diffuse large B-cell lymphoma/High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 translocations (DLBCL/HGBL-MYC/BCL2) represent a distinct and rare diagnostic category in 5th Edition World Health Organization (WHO-HAEM5) classification.
Nuray Bassullu +4 more
doaj +1 more source