Results 111 to 120 of about 179,498 (360)

Data from Modulation of Navitoclax Sensitivity by Dihydroartemisinin-Mediated MCL-1 Repression in BCR-ABL⁺ B-Lineage Acute Lymphoblastic Leukemia

, 2023
Amit Budhraja, Meghan E. Turnis, Michelle L. Churchman, Anisha Kothari, Xue Yang, Haiyan Xu, Ewa Kamińska, John C. Panetta, David Finkelstein, Charles G. Mullighan, Joseph T. Opferman   +10 more
openalex   +1 more source

Reviewer #2 (Public Review): RAG1 and RAG2 non-core regions are implicated in the leukemogenesis and off-target V(D)J recombination in BCR-ABL1-driven B cell lineage lymphoblastic leukemia

, 2023
Xiaozhuo Yu, Wen Zhou, Xiaodong Chen, Shunyu He, Mengting Qin, Meng Yuan, Yang Wang, Woodvine otieno Odhiambo, Yinsha Miao, Yanhong Ji   +9 more
openalex   +1 more source

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

Medicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino, Manuela Bartolini, Rudolf Andrys, Kamil Musilek   +3 more
wiley   +1 more source

Diagnosis and management of biochemical recurrence in patients with prostate cancer who received definitive treatment

Urology Research and Practice, 2019
After definitive treatment, recurrence is seen in some patients, as manifested by a rise in prostate-specific antigen (PSA) before clinical progression.
Hasan Soydan, Kadir Baykal
doaj   +2 more sources

The molecular signature of BCR::ABLP210 and BCR::ABLT315I in a Drosophila melanogaster chronic myeloid leukemia model

iScience
Summary: Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder resulting from a balanced translocation leading to BCR::ABL1 oncogene with increased tyrosine kinase activity.
Amro Baassiri, Ali Ghais, Abdallah Kurdi, Elias Rahal, Rihab Nasr, Margret Shirinian   +5 more
doaj   +1 more source

Evaluation of Morpholino Antisense Oligos’ Role on BCR-ABL Gene Silencing in the K562 Cell Line [PDF]

Cell Journal, 2010
Objective: Chronic myeloid leukemia (CML) develops when a hematopoietic stem cellacquires the BCR/ABL fusion gene. This causes these transformed hematopoietic cellsto have a greater than normal proliferation rate.
Bahman Delalat, Soraya Rasi Ghaemi, Saeid Abroun, Mehrdad Noruzinia, Mahmoud Haririan, Masoud Soleimani, Saeid Kaviani   +6 more
doaj  

Detection of minimal residual bcr/abl transcripts by a modified polymerase chain reaction [PDF]

, 1988
MS Lee, KS Chang, EJ Freireich, HM Kantarjian, Moshe Talpaz, JM Trujillo, SA Stass   +6 more
openalex   +1 more source

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.

New England Journal of Medicine, 2001
B. Druker, M. Talpaz, D. Resta, B. Peng, E. Buchdunger, J. Ford, N. Lydon, H. Kantarjian, R. Capdeville, Sayuri Ohno-Jones, C. Sawyers   +10 more
semanticscholar   +1 more source

Impact of COVID‐19 and Vaccination on Lower Urinary Tract Symptoms: Insights From a Prospective Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza, Jose de Bessa Jr., Natássia Cristina Carboni Truzzi, Carolina Trigo Rocha, Bruno Camargo Rocha Paim de Araujo, Julyana Kanate Mazzoni Moromizato, Thulio Bosi Vieira Brandão, Rachel Mazoni Costa, Marcelo Hisano, Zein Mohamed Sammour, Homero Bruschini, William Carlos Nahas, Cristiano Mendes Gomes   +12 more
wiley   +1 more source

Lack of imprinting of BCR [PDF]

Nature Genetics, 1994
G J, Riggins, F, Zhang, S T, Warren
openaire   +2 more sources