Results 101 to 110 of about 290,825 (294)

High-Level Expression, Purification and Characterization of A Recombinant Plasmodium vivax Apical Membrane Antigen 1: Implication for vivax Malaria Vaccine Development

Cell Journal, 2015
Objective: The apical membrane antigen-1 (AMA-1) is considered as a promising candidate for development of a malaria vaccine against Plasmodium parasites.
Maryam Salavatifar, Sedigheh Zakeri, Nasim Hayati Roodbari, Navid Dinparast Djadid   +3 more
doaj  

Box-Behnken Design-Based Optimization and Evaluation of Lipid-Based Nano Drug Delivery System for Brain Targeting of Bromocriptine

Pharmaceuticals
Bromocriptine (BCR) presents poor bioavailability when administered orally because of its low solubility and prolonged first-pass metabolism. This poses a significant challenge in its utilization as an effective treatment for managing Parkinson’s disease
Asha Spandana K M, Mohit Angolkar, Mohamed Rahamathulla, Kamal Y. Thajudeen, Mohammed Muqtader Ahmed, Syeda Ayesha Farhana, Thippeswamy Boreddy Shivanandappa, Sharanya Paramshetti, Riyaz Ali M. Osmani, Jawahar Natarajan   +9 more
doaj   +1 more source

The precision electroweak data in warped extra-dimension models

, 2008
The Randall-Sundrum scenario with Standard Model fields in the bulk and a custodial symmetry is considered. We determine the several minimal quark representations allowing to address the anomalies in the forward-backward b-quark asymmetry A^b_FB, while ...
Aaltonen, Agashe, Agashe, Agashe, Agashe, Agashe, Agashe, Agashe, Agashe, Agashe, Agashe, Agashe, Agashe, Aihara, Alcaraz, Alcaraz, Altarelli, Altarelli, Altarelli, Althoff, Appelquist, Arkani-Hamed, Awramik, Awramik, Barbieri, Bhattacharyya, Boulware, Brooijmans, Burdman, Burkhardt, Bélanger, Cacciapaglia, Carena, Carena, Carena, Carena, Carena, Carena, Carena, Carena, Casagrande, Chang, Chanowitz, Charles Bouchart, Choudhury, Contino, Contino, Contino, Contino, Csáki, Csáki, Csáki, Csáki, Csáki, Csáki, Davoudiasl, Davoudiasl, Davoudiasl, Degrassi, del Aguila, Dennis, Djouadi, Djouadi, Djouadi, Djouadi, Djouadi, Djouadi, Elsen, Falkowski, Fitzpatrick, Fusaoka, Gherghetta, Gherghetta, Gogberashvili, Grossman, Grégory Moreau, Gubser, Guchait, Hewett, Huber, Huber, Huber, Huber, Huber, Inoue, Ledroit, Lillie, Lillie, Lillie, Maksymyk, Maldacena, Maldacena, Monig, Moreau, Moreau, Moreau, Perez, Peskin, Peskin, Pomarol, Randall, Randall, Randall, Santiago, Shimonoka, Steinhauser, Witten   +106 more
core   +3 more sources

Stafib‐2‐CR: an Improved Nanomolar and Selective Inhibitor of the Transcription Factor STAT5b Developed by Conformational Restriction of Stafib‐2

Chemistry – A European Journal, EarlyView.
Conformational restriction strategies to increase the activity and selectivity of the STAT5b inhibitor Stafib‐2 are presented. The best conformationally restricted inhibitor Stafib‐2‐CR has threefold higher activity against STAT5b than Stafib‐2. A cell‐permeable prodrug of Stafib‐2‐CR inhibits phosphorylation of STAT5b in cultured human leukemia cells ...
Theresa Münzel, Angela Berg, Christoph Protzel, Sylvie Schäfer, Alexander Jensen‐Feinhals, Thorsten Berg   +5 more
wiley   +1 more source

BCR (breakpoint cluster region) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on BCR (breakpoint cluster region), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +3 more sources

Mechanism of Magnetic Flux Loss in Molecular Clouds

, 2002
We investigate the detailed processes working in the drift of magnetic fields in molecular clouds. To the frictional force, whereby the magnetic force is transmitted to neutral molecules, ions contribute more than half only at cloud densities $n_{\rm H} <
Bonnor W. B., de Boisanger C., Ebert R., Mestel L., Nakano T., Nakano T., Nakano T., Nakano T., Nakano T., Nakano T., Nakano T., Nakano T., Ryoichi Nishi, Strittmatter P. A., Takenori Nakano, Toyoharu Umebayashi, Umebayashi T., Umebayashi T., Umebayashi T.   +18 more
core   +1 more source

Monocyte maturation pattern by flow cytometry expression of CD64, CD300e, and CD14 correlates to presence of myeloid neoplasm and helps identify blast equivalents in the setting of monocytic neoplasm

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract CD300e is a marker of mature monocytes in flow cytometry; however, there is limited detailed information on staining patterns in conjunction with other monocyte markers. We evaluated the flow cytometric staining patterns of CD64, CD14, and CD300e in 12 negative and 33 positive peripheral blood specimens and 16 negative and 56 positive bone ...
Jenny Zhang, Jacob Kaplan, Elizabeth Courville   +2 more
wiley   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

BCR-ABL1 genomic DNA PCR response kinetics during first-line imatinib treatment of chronic myeloid leukemia

Haematologica, 2018
Accurate quantification of minimal residual disease (MRD) during treatment of chronic myeloid leukemia (CML) guides clinical decisions. The conventional MRD method, RQ-PCR for BCR-ABL1 mRNA, reflects a composite of the number of circulating leukemic ...
Ilaria S. Pagani, Phuong Dang, Ivar O. Kommers, Jarrad M. Goyne, Mario Nicola, Verity A. Saunders, Jodi Braley, Deborah L. White, David T. Yeung, Susan Branford, Timothy P. Hughes, David M. Ross   +11 more
doaj   +1 more source

Mechanism of stimulated Hawking radiation in a laboratory Bose-Einstein condensate

, 2017
We model a sonic black hole analog in a quasi one-dimensional Bose-Einstein condensate, using a Gross-Pitaevskii equation matching the configuration of a recent experiment by Steinhauer [Nat. Phys. 10, 864 (2014)].
Clark, Charles W., Edwards, Mark, Jacobson, Ted, Wang, Yi-Hsieh   +3 more
core   +1 more source