Results 171 to 180 of about 288,388 (279)

Asciminib and pulsed ATRA as post-remission therapy in T315I mutated PML-RARA-positive blast crisis of chronic myeloid leukemia. [PDF]

Ann Hematol
Mazzarella R, Cicconi L, Perrone S, Divona MD, Ceccolini S, Nardozza AM, Biagi A, Ottone T, Corbingi A, Panetta P, La Barbera EO, Fiori L, Romeo AA, Pacitto G, Cotroneo E, Breccia M, Voso MT, Pulsoni A.   +17 more
europepmc   +1 more source

IRF4 Enhances Radiosensitivity of Cervical Cancer by Inhibiting the PI3K/Akt/mTOR Pathway to Regulate Autophagy

Cancer Science, EarlyView.
IRF4 is a prognostic biomarker in cervical cancer. IRF4 enhances radiosensitivity and inhibits tumor growth via PI3K/AKT/mTOR‐mediated autophagy. IRF4 boosts radiation response in vitro and in vivo. ABSTRACT Interferon regulatory factor 4 (IRF4), a critical member of the IRF transcription factor family, harbors an elusive biological role in cervical ...
Meihui Gao, Zhaolei Cui, Huachun Song, Yanhong Li, Anyang Li, Jianfeng Zheng, Linying Liu, Xuefen Lin, Wankai Fu, Yang Sun   +9 more
wiley   +1 more source

Use of the blood urea nitrogen level to predict the rebleeding in patients with non-variceal upper gastrointestinal bleeding. [PDF]

Medicine (Baltimore)
Lee JS, Kim KB, Yoon SM.
europepmc   +1 more source

Clinical Applications of Phosphoproteomics: Illuminating Cancer Signaling and Enabling Rational Therapeutic Strategies

Cancer Science, EarlyView.
Mass spectrometry‐based phosphoproteomics for mechanistic dissection of cancer signaling pathways and uncovering therapeutic vulnerabilities. ABSTRACT Protein phosphorylation is a central post‐translational modification regulating cellular signaling, frequently dysregulated in cancer.
Hirokazu Shoji, Narikazu Boku, Jun Adachi   +2 more
wiley   +1 more source

Impact of positive surgical margin location on biochemical recurrence in pT3 prostate cancer after robot-assisted radical prostatectomy: a retrospective cohort study. [PDF]

BMC Urol
Altay MS, Kocatürk H, Bedir B, Bedir F, Cinislioğlu AE, Yeğen AF, Aydin Ö, Canda AE, Balbay MD.   +8 more
europepmc   +1 more source

Predictive value of MRD monitoring by BCR clonality in the ZUMA‐7 randomized clinical trial for CAR T therapy in r/r lymphoma

British Journal of Haematology, EarlyView.
Brodie Miles, Daqin Mao, Saran Vardhanabhuti, Davide Bedognetti, Simone Filosto, Rhine Shen   +5 more
wiley   +1 more source

Roles of TIF1β in Leukemic Stem Cell Through SETDB1‐Dependent and Independent Mechanisms

Cancer Science, EarlyView.
In leukemic stem cell, BCR::ABL cooperates with TIF1β to open chromatin at oncogenes and close chromatin at differentiation regulators, driving leukemic reprogramming. In TIF1β‐deficient stem cell, the loss of TIF1β inverts this balance, showing closed chromatin at oncogenes and open chromatin at differentiation regulators.
Mariko Morii, Sho Kubota, Goro Sashida
wiley   +1 more source

Ring finger protein 213 regulates B-cell receptor signaling, metabolism, and development in B lymphocytes. [PDF]

Signal Transduct Target Ther
Zhang Z, Xiang N, Liu Q, Li Y, Wang L, Yang X, Liu J, Zhang L, Lu L, Liang Y, Yang L, Qi X, Liu C.   +12 more
europepmc   +1 more source

Polycythaemic panmyelosis in chronic myeloid leukaemia

British Journal of Haematology, EarlyView.
George Mason, Ameya Hanamshet, Sewon Kim, Nisha Singh, Kirsten McIlroy, Matthew Greenwood   +5 more
wiley   +1 more source

Genomic Profiling in Localized Prostate Cancer: Associations With Biochemical Recurrence and Response to Salvage Radiotherapy

Cancer Science, EarlyView.
Early screening for somatic alterations in localized prostate cancer could help predict biochemical recurrence risk and optimize salvage therapy selection. ABSTRACT The clinical significance of comprehensive genomic profiling (CGP) has been established in metastatic castration‐resistant prostate cancer (PC).
Kenji Zennami, Tetsuya Takimoto, Takuhisa Nukaya, Makoto Sumitomo, Mayu Takeda, Eiji Sugihara, Hideyuki Saya, Ryoichi Shiroki   +7 more
wiley   +1 more source