Results 241 to 250 of about 288,388 (279)

Potential utility of PPARγ agonists in targeting chronic myeloid leukemia stem cells. [PDF]

Ann Hematol
Atef B, El-Ashwah S, Saleh LM, Gawish H, Mabed M.   +4 more
europepmc   +1 more source

Unique chicken B cell development: species-specific mechanisms and contradictory requirements of B cell receptor for post-hatched B cell development. [PDF]

Front Immunol
Woo SJ, Songodan T, Han JY.
europepmc   +1 more source

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CRKL Binding to BCR-ABL and BCR-ABL Transformation

Leukemia & Lymphoma, 1999
The SH2-SH3 domain-containing adaptor protein CRKL is the predominant tyrosine phosphorylated protein in chronic myelogenous leukemia (CML) neutrophils and BCR-ABL-expressing cell lines. The amino terminal CRKL SH3 domain binds directly to a proline-rich region in the C-terminus of BCR-ABL. BCR-ABL mutants with deletions of this region were constructed
K S, Kolibaba, A, Bhat, C, Heaney, T, Oda, B J, Druker   +4 more
openaire   +2 more sources

BCR

2008
The primary structure of Bcr PH domain is analyzed by using biological databank. To obtain the experimental secondary structure content of the recombinant PH protein, CD spectra were measured at 200???240 nm. The data observed correlate to ones for PH domains with determined structure.
openaire   +3 more sources

������������ ������ ���������������������� ���������������� BCR ������ ������������ ���������������������������� ������������������

2010
: (i) M/MD
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Minor BCR (m-bcr) rearrangements may appear in major BCR (M-bcr)-positive CML cases.

Hematologic pathology, 1993
The chromosome 22 derivative, the Philadelphia (Ph) chromosome, results from the reciprocal translocation t(9;22) (q34;q11). On DNA level a BCR/ABL rearrangement involving the so-called major BCR (Mbcr) from chromosome 22 has been associated with chronic myeloid leukemia (CML).
H, Karlic, R, Grill, E, Schlögl
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???????????????? ???????????? DH/PH ?????????????? ?????????? Bcr ???? ?????????????????????? ?????????????????????? ???????????????????????? Bcr-Abl

2021
?????????????? ?????????????? DH, PH ?????????????? Bcr ?????????? ???? ?????????????????????? Bcr-Abl ?? ????????????. ??????????????????????, ?????? ?????????????? PH ???????????? ???????????????????? ?????????????????????????????? ?????????????????????? ?????????? ??????????, ?????????????????????????? ?????? ???????????????????????????? ?? ?????????
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???????????????? bcr ?????????????? ???????????????????? ???????? bcr-abl ???? ???????? ???? ?????????????????? ???????????????????? ???????????????? ?????? ???????????????????????? (9:22)

2021
Bcr ???????????????? ?????????????????? ???????????? ???????????????????? ???????? bcr-abl, ?????????????????????????? ?????? ?????????????????? t(9;22). ???????????? ???? ???????????????? ???????????????????????? ???????????????? ???????????????????????? ?????????????? ?? ???????????????? ??????????????????????. ?? ???????????? ?? ?????????????? ??????
openaire   +1 more source