ABSTRACT Background Hypofractionated salvage radiotherapy is increasingly used for biochemical recurrence of prostate cancer post‐prostatectomy, yet its toxicity profile remains underexplored. This study evaluates the incidence, timing, and resolution of treatment‐related toxicities in this setting.
Bum‐Sup Jang +2 more
wiley +1 more source
Identification of Predictive Biomarkers Based on Cytokine Profiles for Molecular Relapse After Treatment-Free Remission in Chronic Myeloid Leukemia Patients. [PDF]
Vasconcelos Cordoba B +33 more
europepmc +1 more source
Cognitive Rehabilitation Interventions in the Intensive Care Unit: A Systematic Integrative Review
ABSTRACT Background Because critical illness, sedation, and ICU treatment commonly disrupt attention, memory, and executive function, early cognitive rehabilitation during the ICU stay may preserve or restore these capacities, reduce the delirium burden, and support engagement and recovery.
Kamila C. Lassen +14 more
wiley +1 more source
BCR::ABL1 tyrosine kinase inhibitors induce ribosome collisions to activate ZAK-dependent ribotoxic stress and apoptosis in chronic myeloid leukemia. [PDF]
Park J +6 more
europepmc +1 more source
Developing a Core Outcome Measurement Set for Adult ICU Patients, the CoreMS‐ICU—A Protocol
ABSTRACT Background Core outcome measurement sets (COMS) enhance the consistency and comparability of outcome reporting in clinical research. However, their effectiveness depends on the selection of valid, reliable, and feasible measurement instruments.
Maj‐Brit Nørregaard Kjær +53 more
wiley +1 more source
Langerhans Cell Histiocytosis Associated With Chronic Myeloid Leukemia: A Pediatric Case Report. [PDF]
Latifi A, Yousefian S.
europepmc +1 more source
Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren +8 more
wiley +1 more source
Targeting leukemic stem and progenitor cells expressing different BCR::ABL1 levels: antileukemic activity of asciminib with or without TKIs. [PDF]
Massimino M +9 more
europepmc +1 more source

