Results 81 to 90 of about 9,946,516 (158)

A comprehensive regulatory and industry review of modeling and simulation practices in oncology clinical drug development. [PDF]

J Pharmacokinet Pharmacodyn, 2023
Ruiz-Garcia A, Baverel P, Bottino D, Dolton M, Feng Y, González-García I, Kim J, Robey S, Singh I, Turner D, Wu SP, Yin D, Zhou D, Zhu H, Bonate P.   +14 more
europepmc   +1 more source

A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins [PDF]

, 2011
Mutations of human leucine-rich glioma inactivated (LGI1) gene encoding the epitempin protein cause autosomal dominant temporal lateral epilepsy (ADTLE), a rare familial partial epileptic syndrome.
Leonardi, Emanuela, Tosatto, Silvio C. E., Giorgia Busolin, Simonetta Andreazza, Busolin, Giorgia, Tosatto, Silvio C E, Emanuela Leonardi, Carlo Nobile, Silvio C E Tosatto, TOSATTO, SILVIO, Busolin Giorgia, Silvio C. E. Tosatto, Tosatto Silvio C. E., Vanin, Stefano, Vanin Stefano, NOBILE C, Langowski, Jörg, Stefano Vanin, Andreazza Simonetta, Andreazza, Simonetta, Nobile, Carlo, ANDREAZZA A, Leonardi Emanuela, Nobile Carlo   +23 more
core   +1 more source

Protein reconstitution and three-dimensional domain swapping: Benefits and constraints of covalency

, 2007
The phenomena of protein reconstitution and three-dimensional domain swapping reveal that highly similar structures can be obtained whether a protein is comprised of one or more polypeptide chains.
Jannette Carey, Carey, Jannette, Linse, Sara,, Mikael Bauer, Lindman, Stina,, Bauer, Mikael,, Lindman, Stina, Bauer, Mikael, Sara Linse, Linse, Sara, Lund University., Stina Lindman   +11 more
core   +1 more source

Pleural effusion in hematological pathology. [PDF]

Cytojournal, 2021
Yerrapotu N, Rahman A, Gabali A, Shidham VB.   +3 more
europepmc   +1 more source

Excessive concentrations of kinase inhibitors in translational studies impede effective drug repurposing. [PDF]

Cell Rep Med, 2023
Liu C, Leighow SM, McIlroy K, Lu M, Dennis KA, Abello K, Brown DJ, Moore CJ, Shah A, Inam H, Rivera VM, Pritchard JR.   +11 more
europepmc   +1 more source

Steered Molecular Dynamics Simulations Study on FABP4 Inhibitors. [PDF]

Molecules, 2023
Tomarchio R, Patamia V, Zagni C, Crocetti L, Cilibrizzi A, Floresta G, Rescifina A.   +6 more
europepmc   +1 more source

Cardiovascular Issues in Tyrosine Kinase Inhibitors Treatments for Chronic Myeloid Leukemia: A Review. [PDF]

Front Physiol, 2021
Santoro M, Mancuso S, Accurso V, Di Lisi D, Novo G, Siragusa S.   +5 more
europepmc   +1 more source

Iron Deficiency Caused by Intestinal Iron Loss-Novel Candidate Genes for Severe Anemia. [PDF]

Genes (Basel), 2021
Huettmann C, Stelljes M, Sivalingam S, Fobker M, Vrachimis A, Exler A, Wenning C, Wempe C, Penke M, Buness A, Ludwig KU, Muckenthaler MU, Steinbicker AU.   +12 more
europepmc   +1 more source

Establishment of a FDC-P1 Murine Cell Line with Human KIT N822K Gene Overexpression. [PDF]

Acta Naturae, 2020
Vagapova ER, Lebedev TD, Popenko VI, Leonova OG, Spirin PV, Prassolov VS.   +5 more
europepmc   +1 more source

Omacetaxine may have a role in chronic myeloid leukaemia eradication through downregulation of Mcl-1 and induction of apoptosis in stem/progenitor cells

Leukemia, 2011
EK Allan, TL Holyoake, A. Craig, HG Jørgensen   +3 more
semanticscholar   +1 more source