Results 71 to 80 of about 238 (95)

On the low reproducibility of cancer studies. [PDF]

Natl Sci Rev, 2018
Wen H, Wang HY, He X, Wu CI.
europepmc   +1 more source

Phase II trial of dasatinib for recurrent or metastatic c-KIT expressing adenoid cystic carcinoma and for nonadenoid cystic malignant salivary tumors. [PDF]

Ann Oncol, 2016
Wong SJ, Karrison T, Hayes DN, Kies MS, Cullen KJ, Tanvetyanon T, Argiris A, Takebe N, Lim D, Saba NF, Worden FP, Gilbert J, Lenz HJ, Razak AR, Roberts JD, Vokes EE, Cohen EE.   +16 more
europepmc   +1 more source

Mechanistic Insights into Alternative Gene Splicing in Oxidative Stress and Tissue Injury. [PDF]

Antioxid Redox Signal
Dery KJ, Wong Z, Wei M, Kupiec-Weglinski JW.   +3 more
europepmc   +1 more source

Use of deferasirox, an iron chelator, to overcome imatinib resistance of chronic myeloid leukemia cells. [PDF]

Korean J Intern Med, 2016
Kim DS, Na YJ, Kang MH, Yoon SY, Choi CW.   +4 more
europepmc   +1 more source

Single-cell multiomics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response. [PDF]

Elife
Warfvinge R, Geironson Ulfsson L, Dhapola P, Safi F, Sommarin M, Soneji S, Hjorth-Hansen H, Mustjoki S, Richter J, Thakur RK, Karlsson G.   +10 more
europepmc   +1 more source

Giant aortic aneurysm due to fibulin- 4 deficiency: case series. [PDF]

Turk Pediatri Ars, 2019
Sülü A, Başpınar O, Şahin DA.
europepmc   +1 more source

Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy. [PDF]

Oncotarget, 2011
Chomel JC, Turhan AG.
europepmc   +1 more source

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Antagonistic Effects of ABL and BCRABL Proteins on Proliferation and the Response to Genotoxic Stress in Normal and Leukemic Myeloid Cells

Leukemia & Lymphoma, 1998
Following the discovery of the p210bcrabl protein product of the bcrabl chimeric fusion gene generated by the Philadelphia chromosome translocation in chronic myelogenous leukemia (CML), structure function studies quickly identified which parts of this molecule were playing a role in the generation of the phenotypes of growth factor independent growth,
X Y, Guo, J, Fontana, D, Kufe, A, Deisseroth   +3 more
openaire   +4 more sources

Ribozyme-mediated cleavage of the BCRABL oncogene transcript: in vitro cleavage of RNA and in vivo loss of P210 protein-kinase activity.

Oncogene, 1993
The t(9,22) chromosomal translocation generating the Philadelphia chromosome and the BCRABL oncogene has been shown both cytogenetically and molecularly to be the etiologic event in chronic myelogenous leukemia (CML). We have designed a ribozyme to cleave the BCRABL mRNA by targeting a GUU triplet adjacent to the junction of the c-BCR and c-ABL fused ...
S K, Shore, P M, Nabissa, E P, Reddy
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Presence of P210bcrabl Is Associated with Decreased Expression of a Beta Chemokine C10 Gene in a P210bcrabl-Positive Myeloid Leukemia Cell Line

Molecular Medicine, 1999
Deisseroth Albert B
exaly