Resampling-Based Multiple Hypothesis Testing with Applications to Genomics: New Developments in the R/Bioconductor Package multtest [PDF]
, 2009 The multtest package is a standard Bioconductor package containing a suite of functions useful for executing, summarizing, and displaying the results from a wide variety of multiple testing procedures (MTPs).
Dudoit, Sandrine +3 more
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Coexistence of P190 and P210 BCR/ABL transcripts in chronic myeloid leukemia blast crisis resistant to imatinib [PDF]
, 2015 Introduction Philadelphia chromosome (Ph) is a hallmark of chronic myeloid leukemia (CML), which exists in more than 90% CML and in 3% to 40% acute lymphoblastic leukemia (ALL). Case description A
Fang Baijun +6 more
core +1 more source
Loss of PDZK1 expression activates PI3K/AKT signaling via PTEN phosphorylation in gastric cancer [PDF]
, 2019 Phosphorylation of PTEN plays an important role in carcinogenesis and progression of gastric cancer. However, the underlying mechanism of PTEN phosphorylation regulation remains largely elusive.
Feng, Duiping +16 more
core +2 more sources
Masked inv dup(22)(q11.23), tetrasomy 8 and trisomy 19 in a blast crisis-chronic myeloid leukemia after interrupted Imatinib-treatment [PDF]
, 2015 BACKGROUND: The Philadelphia (Ph) chromosome, or derivative chromosome 22 [der(22)], is a product of the reciprocal translocation t(9;22). It is the hallmark of chronic myelogenous leukemia (CML).
Abdulsamad Wafa +3 more
core +1 more source
Thymoquinone Induces Downregulation of BCR-ABL/JAK/STAT Pathway and Apoptosis in K562 Leukemia Cells. [PDF]
Asian Pac J Cancer Prev, 2021 Al-Rawashde FA +5 more
europepmc +1 more source
LEUCEMIA MIELOIDE CRÓNICA(PH+): DIAGNÓSTICO Y TRATAMIENTO [PDF]
, 2015 Chronic myelogenous leukemia is considered as an exemplary for the development of molecular targeted therapies due to its pathogenesis. This disease is characterized by the presence of Philadelphia chromosome (PH+), a product of the reciprocal ...
García Fallas, Miriam
core +1 more source
Bedeutung der Rezeptor-Tyrosinkinase c-Kit in der Pathogenese der, Philadelphiatranslokation Bcr-Abl positiven, chronischen myeloischen Leukämie [PDF]
, 2003 Die vorliegende Arbeit beschreibt die durchgeführten Experimente zur Charakterisierung der molekularen Assoziation der Rezeptor-Tyrosinkinase c-Kit mit dem Onkoprotein Bcr-Abl.
Konieczny, Andreas
core
Disease modification trials in parkinsons disease: A Review [PDF]
, 2020 Among the common neurological disorders worldwide, Parkinson’s disease has a major share. Currently, only symptomatic therapies are available for it without any approved neuromodulation drugs as all the previously done disease modification trials have ...
Hashmi, Ramla Nayaib, Kiram, Ummul
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