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, 2014 实验目的 卵巢癌是女性生殖系统常见的三大癌症之一，病死率居妇科癌症首位。其早期症状隐匿、易发生多脏器移植、淋巴结转移，确诊时70%已属晚期，5年生存率低。卵巢癌的侵袭及转移是造成其治疗困难、病死率高的主要原因。原癌基因Wnt信号通路在胚胎发育、干细胞、免疫系统以及肿瘤发生等生理病理过程中发挥重要作用。作为Wnt信号通路的辅助受体，低密度脂蛋白受体相关蛋白5（low density lipoprotein receptor related – protein 5 LRP5）与肿瘤的浸润转移密切相关 ...
马玉玲
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, 1987 <正> “中国光纤通信线路分布示意图”的按语现在,我国的光纤通信技术已趋于成熟,开始步入应用推广时期。到1986年底,全国已敷设公用通信网光缆线路近700km,安装了约30个光纤通信系统。其中,北京、上海、武汉、广州等地有多个光纤通信系统已投入使用。当然,就线路长度而言,多为短距离的。预计“七五”期间还要敷设4000km长途光缆线路 ...
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[Huangpu Tongqiao Capsule improves cognitive impairment in rats with Wilson disease by inhibiting endoplasmic reticulum stress-mediated apoptosis pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhang X +5 more
europepmc +1 more source
"Abstracts of the 77th Annual Meeting of the Japanese Cancer Association; 2018 Sept 27-29; Osaka, Japan" as Cancer Science, Supplement 2, Vol 109 (2018). [PDF]
Cancer Sci, 2018 europepmc +1 more source
BDNF-TrkB signaling orchestrates the buildup process of local sleep [PDF]
Cell ReportsSleep debt accumulates during wakefulness, leading to increased slow wave activity (SWA) during sleep, an encephalographic marker for sleep need. The use-dependent demands of prior wakefulness increase sleep SWA locally.
Waleed Elgrawani
exaly +2 more sources
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Regulation of BDNF-TrkB Signaling and Potential Therapeutic Strategies for Parkinson’s Disease
Journal of Clinical Medicine, 2020Wook Jin, Jin Wook
exaly
Constitutive BDNF/TrkB signaling is required for normal cardiac contraction and relaxation
Proceedings of the National Academy of Sciences of the United States of America, 2015Ning Feng +2 more
exaly
Function and Mechanisms of Truncated BDNF Receptor TrkB.T1 in Neuropathic Pain
Cells, 2020Cynthia L Renn +2 more
exaly