Results 231 to 240 of about 122,805 (310)

KREO Prevents CUMS-Induced Depressive-Like Behavior via Modulation of the BDNF Signaling Pathway. [PDF]

Food Sci Nutr
Wang Y, Yue Z, Xu M, Xu W, Zhang W, Li X, Liu Q, Guan K, Zhang Z, Li Y, Wang X, Li H.   +11 more
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

TrkB/mGluR5 cross-talk underlies a synaptic metaplasticity mechanism of ketamine. [PDF]

Sci Adv
Arefin A, Kim J, Chakraborty MP, Martinelli S, Bai B, Lee FS, Levitz J.   +6 more
europepmc   +1 more source

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

The Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

BDNF insufficiency exacerbates ALS progression. [PDF]

Cell Rep Med
Xu Y, He J, Wang S, Ge Y, Jia Y, Guo W, Lv C, Yao X, Mao Y, Mei F, Fan D, Yuan P, Lu B.   +12 more
europepmc   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

Effects of neuroinflammation and neurotrophic factors on mental health of people with axial spondyloarthritis. [PDF]

Brain Behav Immun Health
Hušáková M, Pavelka K, Kuchaříková K, Kotrs J, Balajková V, Kuklová M, Škubica P, Hulejová H, Šenolt L, Mohr P, Olejárová M.   +10 more
europepmc   +1 more source

Transcutaneous auricular vagus nerve stimulation during short‐term motor practice drives cortical plasticity without behavioural improvement

The Journal of Physiology, EarlyView.
Abstract figure legend Transcutaneous auricular vagus nerve stimulation (taVNS) was applied during short‐term dexterous motor practice to examine its effects on behavioural performance and neural plasticity. Healthy participants practiced a two‐ball rotation task while receiving taVNS or sham stimulation.
Kento Nakagawa, Rieko Osu
wiley   +1 more source

BDNF Protects Against Neuronal Damage Induced by TNF and β-Amyloid Peptides by Targeting JNK Activation. [PDF]

Neurochem Res
Ramírez-Olvera A, Almazán JL, Pérez-Martínez L, Pedraza-Alva G.   +3 more
europepmc   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source