Results 261 to 270 of about 197,182 (311)

Microglial Expression of Serotonin Receptors Reveals Parallel Regulation of 5-HT2b and BDNF in the Rat Hippocampus. [PDF]

Cells
Turkin A, Sidorova M, Kurilova E, Alenina N, Tuchina O, Klempin F.   +5 more
europepmc   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

Cang-Ai Volatile Oil Mitigates Lipopolysaccharide-Induced Depressive-Like Behaviour in Mice by Modulating the Microglial BDNF/CREB Signaling Pathway. [PDF]

Mol Neurobiol
Zhao L, Yin R, Zhang K, Huang J, Zheng R, Zhu Y, Li G, Lei N, Xiong L, Xie Y.   +9 more
europepmc   +1 more source

Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age‐related processes leading to Porphyr'ageing

International Journal of Cosmetic Science, EarlyView.
Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier, Morgane De Tollenaere, Cyrille Jarrin, Emilie Chapuis, Marine Bracq, Laura Lapierre, Catherine Zanchetta, Jean Tiguemounine, Amandine Scandolera, Romain Reynaud   +9 more
wiley   +1 more source

Cognitive subgroups in bipolar disorder: associations with brain-derived neurotrophic factor and C-reactive protein. [PDF]

BJPsych Open
Demir AM, Görgülü Y, Söğüt K, Palabıyık O, Ayduk Gövdeli E.   +4 more
europepmc   +1 more source

Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect

Journal of Child Psychology and Psychiatry, EarlyView.
Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson, Hanna R. Wright, Jorden E. Jacinto Schreeder, Joel T. Nigg, Elinor L. Sullivan   +4 more
wiley   +1 more source

BDNF in ventrolateral orbitofrontal cortex to dorsolateral striatum circuit moderates alcohol consumption, seeking and relapse. [PDF]

Neuropsychopharmacology
Gunasekaran S, Moffat JJ, Epstein JD, Phamluong K, Ehinger Y, Ron D.   +5 more
europepmc   +1 more source

Practitioner Review: Infant mental health meets cell and molecular biology – a look to the future

Journal of Child Psychology and Psychiatry, EarlyView.
Background A major research effort in the past two decades has begun to illuminate how experience ‘gets under the skin’ – that is – the cellular and molecular processes that are associated with adversity and resilience. Methods We selectively review three areas of this research: epigenetics, especially DNA methylation, telomere length, and inflammatory
Charles H. Zeanah, Megan Hare, Katherine Cowhey, Stacy S. Drury   +3 more
wiley   +1 more source

Trazodone modulates behavioral alterations in scopolamine-induced cognitive deficit by targeting brain-derived neurotropic factor and cAMP response element-binding protein signaling. [PDF]

Front Cell Neurosci
Dhaka P, Pinky, Neha, Khan MA, Rabbani SA, El-Tanani M, Parvez S.   +6 more
europepmc   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source