Results 21 to 30 of about 220,963 (383)
BDNF and cognitive function in Alzheimer’s disease
European Psychiatry, 2022 Introduction Alzheimer’s disease (AD) is a neurodegenerative pathology that develops mainly in elderly and senile people. Disruption of BDNF transport or suppression of its production appears to be typical for people of old age.
A. Sidenkova
doaj +1 more source
Journal of Neuroinflammation, 2020 Postoperative cognitive decline (POCD) is a recognized clinical phenomenon characterized by cognitive impairments in patients following anesthesia and surgery, yet its underlying mechanism remains unclear.
L. Qiu +7 more
semanticscholar +1 more source
Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function. [PDF]
, 2018 We developed an innovative biomaterial-based approach to repair the critical neural circuitry that controls diaphragm activation by locally delivering brain-derived neurotrophic factor (BDNF) to injured cervical spinal cord.
Ghosh, Biswarup +8 more
core +2 more sources
Examination of BDNF Treatment on BACE1 Activity and Acute Exercise on Brain BDNF Signaling [PDF]
Frontiers in Cellular Neuroscience, 2021 Perturbations in metabolism results in the accumulation of beta-amyloid peptides, which is a pathological feature of Alzheimer’s disease. Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) is the rate limiting enzyme responsible for beta-amyloid production.
Bradley J. Baranowski +4 more
openaire +4 more sources
Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: Implication for neuroprotective therapies [PDF]
, 2013 Neuroprotective therapies based on brain-derived neurotrophic factor (BDNF) administration have been proposed for Huntington's disease (HD) treatment. However, our group has recently reported reduced levels of TrkB in HD mouse models and HD human brain ...
Alberch, J. +5 more
core +1 more source
Relationship between BDNF and oxytocin
Comprehensive Psychoneuroendocrinology, 2023 Converging, albeit scattered data mainly gathered in animals indicate that the neurotrophin brain-derived neurotrophic factor (BDNF) and the nonapeptide oxytocin (OT) interact in a cooperative way. Data in humans are really limited and indirect. Therefore, the aim of the present study was to explore the possible existence of a link between OT and BDNF ...
Marazziti D. +9 more
openaire +4 more sources
Chronic lithium treatment elicits its antimanic effects via BDNF-TrkB dependent synaptic downscaling
eLife, 2017 Lithium is widely used as a treatment for Bipolar Disorder although the molecular mechanisms that underlie its therapeutic effects are under debate.
Erinn S Gideons +4 more
doaj +1 more source
Journal of Diabetology, 2023 Background: Low brain-derived neurotrophic factor (BDNF) has been reported in people with type 2 diabetes mellitus (T2DM). Resistance exercise improves levels of BDNF in T2DM; however, it is unknown what amount of exercise intensity will alter its ...
Sarah Parveen +4 more
doaj +1 more source
A network map of BDNF/TRKB and BDNF/p75NTR signaling system [PDF]
Journal of Cell Communication and Signaling, 2013 Neurotrophic factors are growth factors, which play an essential role in the development and maintenance of nervous system. These include members of the nerve growth factor (NGF) family, known as neurotrophins. Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin 3 (NT-3), neurotrophin 4 (NT4/5) and neurotrophin 6 (NT-6 ...
Kanchan K Mukherjee +12 more
openaire +3 more sources
Surabaya Physical Medicine and Rehabilitation Journal, 2020 Background: Cognitive impairment is the most frequent complication of stroke. However, erobic exercise is considered to have potential effect in inhibiting the post-stroke cognitive degradation and increasing cognitive performance through neuroplasticity-
Vanydia Aisyah +2 more
doaj +1 more source