Results 21 to 30 of about 93,782 (262)

The effect of morphine upon DNA methylation in ten regions of the rat brain

open access: yesEpigenetics, 2017
Morphine is one of the most effective analgesics in medicine. However, its use is associated with the development of tolerance and dependence. Recent studies demonstrating epigenetic changes in the brain after exposure to opiates have provided insight ...
Timothy M. Barrow   +7 more
doaj   +1 more source

BDNF and memory processing [PDF]

open access: yesNeuropharmacology, 2014
Brain-derived neurotrophic factor has emerged as one of the most important molecules involved in memory. Its wide role in different types of memories that depend on different structures as well as its involvement in distinct memory stages points at BDNF as one likely target to treat cognitive impairments and anxiety-related memory disorders.
Bekinschtein, Pedro   +2 more
openaire   +4 more sources

Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study

open access: yesEpigenetics, 2018
Bisphenol A (BPA), an endocrine disrupting chemical (EDC), is a ubiquitous pollutant. As part of the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA), we sought to determine whether exposure of Sprague-Dawley rats to 2 ...
Ana Cheong   +9 more
doaj   +1 more source

Changes in serum brain derived neurotrophic factor following high intensity interval training among obese undergraduates

open access: yesThe Proceedings of the Nigerian Academy of Science, 2021
The study examined changes in Serum Brain Derived Neurotrophic Factor (BDNF) following High Intensity Interval Training (HIIT) programme among obese undergraduates. The pretest-posttest randomized experimental design was employed for the study.
Karl E. Eimuhi   +2 more
doaj   +1 more source

The BDNF rs6265 variant may interact with overweight and obesity to influence obesity-related physical, metabolic and behavioural traits in Pakistani individuals

open access: yesAnnals of Human Biology, 2018
Background: The association of the variant rs6265 (G>A) in the brain-derived neurotrophic factor (BDNF) gene with obesity and other obesity-related parameters is not known for the Pakistani population.
Sobia Rana, Saad Mirza, Soma Rahmani
doaj   +1 more source

The Effect of Pilates Exercises on BDNF Serum Level, Balance and Quality of Life of Menopausal and Non-Menopausal Women [PDF]

open access: yesرشد و یادگیری حرکتی ورزشی
Introduction: Menopause is the beginning of a new era in a woman's life. This period, like all other stages of life, has positive and negative aspects.
sepide jalali   +2 more
doaj   +1 more source

Blood BDNF concentrations reflect brain-tissue BDNF levels across species [PDF]

open access: yesThe International Journal of Neuropsychopharmacology, 2010
Brain-derived neurotrophic factor (BDNF) is involved in synaptic plasticity, neuronal differentiation and survival of neurons. Observations of decreased serum BDNF levels in patients with neuropsychiatric disorders have highlighted the potential of BDNF as a biomarker, but so far there have been no studies directly comparing blood BDNF levels to brain ...
Klein, Anders B   +7 more
openaire   +3 more sources

PTSD risk is associated with BDNF Val66Met and BDNF overexpression [PDF]

open access: yesMolecular Psychiatry, 2013
Brain-derived neurotrophic factor (BDNF), which regulates neuronal survival, growth, differentiation and synapse formation, broadly regulates the stress response.1 A common single-nucleotide polymorphism in the BDNF gene (Val66Met) influences hippocampal volume,2 memory3 and appears related to susceptibility to a variety of neuropsychiatric disorders ...
L, Zhang   +11 more
openaire   +2 more sources

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

The Neurogenic Effects of Pasak bumi (Eurycoma longifolia Jack) and Seluang Fish (Rasbora spp.) in Malnutrition-Induced Rat

open access: yesFolia Medica Indonesiana
Highlights: 1. This study analyzed the effects of using locally sourced pasak bumi extract and seluang fish on the parameters of neurogenesis in malnourished rat models. 2.
Didik Dwi Sanyoto   +3 more
doaj   +1 more source

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