Results 71 to 80 of about 999,841 (275)

Optimization of cell disruption in Raphidocelis subcapitata and Chlorella vulgaris for biomarker evaluation [PDF]

, 2015
Raphidocelis subcapitata and Chlorella vulgaris are bioassay microalgae with rigid cellulosic cell wall which can hinder the release of intracellular proteins often studied as toxicity biomarkers.
Aderemi, Adeolu, Hunter, Colin, Pahl, Ole, Shu, Xinhua   +3 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Annexin-coated particles induce antigen-specific immunosuppression

Autoimmunity, 2020
Apoptotic cells mediate the development of tolerogenic dendritic cells (DC) and thus facilitate induction and maintenance of peripheral tolerance. Following the identification of the evolutionary conserved annexin core domain (Anx) as a specific signal ...
Corinna Link, Fatmire Bujupi, Peter H. Krammer, Heiko Weyd   +3 more
doaj   +1 more source

Spire stimulates nucleation by Cappuccino and binds both ends of actin filaments. [PDF]

, 2020
The actin nucleators Spire and Cappuccino synergize to promote actin assembly, but the mechanism of their synergy is controversial. Together these proteins promote the formation of actin meshes, which are conserved structures that regulate the ...
Bailey, Hannah M, Bradley, Alexander O, Quinlan, Margot E, Vizcarra, Christina L   +3 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Beadwork and the Plasticity of Disability: (Un)Making Bodily Difference, Gender and Apprenticeship in Kinshasa, DR Congo

Societies, 2016
Plastic beads have recently become of importance in the lives of women with disabilities in Kinshasa, Democratic Republic of the Congo (DR Congo).
Jori De Coster, Eric Metho Nkayilu, Patrick Devlieger   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Thiol-Stabilized Copper Sulfide Nanoparticles and Their Incorporation into Alginic Beads for Potential Sorption Applications

Compounds
Antibiotics are increasingly detected in aquatic environments, raising environmental and public health concerns due to their persistence and contribution to antimicrobial resistance.
Dana Ortiz-Ortiz, Sonia J. Bailón-Ruiz
doaj   +1 more source

Glass Beads, Markers of Ancient Trade in Sub-Saharan Africa: Methodology, State of the Art and Perspectives

Heritage, 2019
Glass beads have been produced and traded for millennia all over the world for use as everyday items of adornment, ceremonial costumes or objects of barter.
Farahnaz Koleini, Philippe Colomban, Innocent Pikirayi, Linda C. Prinsloo   +3 more
doaj   +1 more source

A child burial with a necklace from the Triangle cemetery in Prague-Střešovice

Archeologické Rozhledy, 2020
The Triangle cemetery in Prague-Střešovice was the only preserved part of the great burial site from the 9th–10th century AD; this site was partially destroyed beginning in the 18th century by the extraction of clay for the Strahov brick factory.
Drahomíra Frolíková, Estelle Ottenwelter, Ludmila Barčáková   +2 more
doaj   +1 more source