Results 81 to 90 of about 5,346,014 (404)

Aggregate effect on the concrete cone capacity of an undercut anchor under quasi-static tensile load [PDF]

, 2018
In the last decades, fastening systems have become an essential part of the construction industry. Post-installed mechanical anchors are frequently used in concrete members to connect them with other load bearing structural members, or to attach ...
Boumakis, Ioannis, Czernuschka, Lisa-Marie, Marcon, Marco, Nincevic, Kresimir, Wan-Wendner, Roman   +4 more
core   +3 more sources

3D bearing capacity probabilistic analyses of footings on spatially variable c–φ soil

Acta Geotechnica, 2019
The paper examines three-dimensional (3D) analyses of the load bearing capacity of square and strip footings on a spatially variable cohesive–frictional (c–φ) soil. Embedded, rigid and smooth footings are considered.
M. Kawa, W. Puła
semanticscholar   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Forecasting the bearing capacity of the mixed soil using artificial neural network

Fracture and Structural Integrity, 2020
The bearing capacity of soil changes owing to the mechanical properties of the soil and it influences the structural stability. In most of the geotechnical engineering projects, there are several soil mechanic experiments, that need interpretation before
Abdoullah Namdar
doaj   +1 more source

Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody. [PDF]

, 2019
Breast cancers enduring treatment with chemotherapy may be enriched for cancer stem cells or tumor-initiating cells, which have an enhanced capacity for self-renewal, tumor initiation, and/or metastasis.
Carson, Dennis A, Cui, Bing, Ghia, Emanuela M, He, Jinsong, Huang, Jiajia, Jiang, Wenqi, Kipps, Thomas J, Lam, Sharon, Lei, Yang, Messer, Karen, Parker, Barbara A, Schwab, Richard, Widhopf, George F, Wu, Liufeng, Yu, Jian, Zhang, Han, Zhang, Jianchao, Zhang, Suping   +17 more
core   +1 more source

Updating material factors for assessment of historic reinforced concrete bridge [PDF]

, 2016
This paper is focused on the reliability analysis of an existing reinforced concrete bridge from 1908. The load bearing capacity is assessed in accordance with valid standards using updated partial factors and the partial factors for structural design.
Krejsa, Jan, Sýkora, Miroslav
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Aging concrete structures: a review of mechanics and concepts [PDF]

, 2018
The safe and cost-efficient management of our built infrastructure is a challenging task considering the expected service life of at least 50 years. In spite of time-dependent changes in material properties, deterioration processes and changing demand by
Wan-Wendner, Roman
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Evolution Mechanism and Cyclic Degradation Model of Ultimate Bearing Capacity for Suction Caissons Under Inclined Combined Loading

Applied Sciences
In the marine environment, the suction caisson foundation (SCF) is often subjected to combined inclined and cyclic loading from wind and waves, which may significantly affect its ultimate bearing capacity. Under combined loading conditions, the evolution
Kang Huang, Bingzhen Yu, Bo Liu, Liji Huang, Huiyuan Deng, Wenbo Zhu, Guoliang Dai   +6 more
doaj   +1 more source