Results 61 to 70 of about 4,543,198 (309)

Study on constant-resistance energy-absorbing components of hydraulic support for rock burst roadway and their anti-impact performance

Meitan kexue jishu
The significant fluctuation in bearing capacity remains a critical challenge to be addressed in thin-walled corrugated anti-impact energy-absorbing components.
Yimin SONG, Di WU, Dong AN, Hailiang XU, Tengteng WANG, Qiuliang WAN, Tian WEN, Jinying FAN   +7 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Bearing Capacity of very Expansive Soils at Jatinangor Area, West Java, Indonesia

MATEC Web of Conferences, 2018
Expansive soil is a kind of soil that has ability to shrinkage and swelling. According to Ronny (2014) Jatinangor area has expansive soil that is so very influential in the planning of infrastructure construction.
Simangunsong David, Wibowo Satrio, Zakaria Zufialdi   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

LONG BEARING CAPACITY OF WOODEN STRUCTURES

Structural Mechanics of Engineering Constructions and Buildings, 2014
In the work, the solution of a problem of stability of the compressed wooden elements with taking into account nonlinear creep of wood is presented.
A S Varenik, K A Varenik
doaj  

Experimental research and numerical simulation of bearing capacity of high-steep rock foundations near slopes

矿业科学学报
This study conducted bearing capacity test of high-steep rock slope foundation under different slope angles and slope distances to investigate the bearing capacity of high-steep rock slope foundation.
LEI Yong, LIU Zikui, CHEN Yusi, HE Changjie, LI Jianxin   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Undrained bearing capacity of spatially random soil for rectangular footings

Soils and Foundations, 2019
In this study, a new approach for the evaluation of the 3-D random bearing capacity in rectangular footings is described. The soil strength spatial variability is modelled by random fields.
M. Chwała
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

3D bearing capacity probabilistic analyses of footings on spatially variable c–φ soil

Acta Geotechnica, 2019
The paper examines three-dimensional (3D) analyses of the load bearing capacity of square and strip footings on a spatially variable cohesive–frictional (c–φ) soil. Embedded, rigid and smooth footings are considered.
M. Kawa, W. Puła
semanticscholar   +1 more source