Results 51 to 60 of about 4,543,198 (309)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

GAS THRUST BEARING OF INCREASED BEARING CAPACITY WITH YIELDING BEARING SURFACE

open access: yesВестник Донского государственного технического университета, 2018
Basic operation factors of the deformed gas-lubricated thrust bearing with increased bearing capacity are theoretically analysed. It is shown that steady-state operation characteristics of this bearing differ from those of the rigid bearing.
Kamil S. AKHVERDIYEV   +2 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Sustainable Soil Bearing Capacity Improvement Using Natural Limited Life Geotextile Reinforcement—A Review

open access: yesMinerals, 2020
Geotextiles are commercially made from synthetic fibres and have been used to enhance bearing capacity and to reduce the settlement of weak soil foundations. Several efforts have been made to investigate the possibility of using bio-based geotextiles for
Mohammad Shirazi   +6 more
semanticscholar   +1 more source

Experimental investigation of relationship between bearing capacity and vibration parameters for planetary exploration legged rovers

open access: yesROBOMECH Journal, 2023
In recent years, robots with leg mechanisms have received considerable attention as high-running planetary exploration rovers. Rovers undertaking planetary exploration require outstanding running performance to travel on loose ground on which they mostly
Tomohiro Watanabe, Kojiro Iizuka
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

STUDY ON THE AXIAL BEARING CAPACITY OF T AEROSTATIC BEARING

open access: yesJixie qiangdu, 2016
Even a small axial vibration or an axis deflection vibration of the aerostatic bearing of DFC tool can be quite significant for ultra-precision machining. It is of great importance to obtain the accurate axial bearing characteristic( bearing capacity and
ZHAO Gong   +3 more
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Influence of the number of reinforcement layers on the bearing capacity of strip foundation resting on sandy soil

open access: yesAl-Qadisiyah Journal for Engineering Science, 2020
Reinforced soil technology is considered one of the most important methods of soil improvement due to its simplicity, easy implementation and saving cost.
Noor Ali Fakher a   +1 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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