Results 51 to 60 of about 4,493,317 (309)

GAS THRUST BEARING OF INCREASED BEARING CAPACITY WITH YIELDING BEARING SURFACE

Advanced Engineering Research, 2010
Basic operation factors of the deformed gas-lubricated thrust bearing with increased bearing capacity are theoretically analysed. It is shown that steady-state operation characteristics of this bearing differ from those of the rigid bearing.
Kamil S. AKHVERDIYEV, Murman A. MUKUTADZE, Vladimir A. KONSTANTINOV   +2 more
doaj  

Experimental investigation of relationship between bearing capacity and vibration parameters for planetary exploration legged rovers

ROBOMECH Journal, 2023
In recent years, robots with leg mechanisms have received considerable attention as high-running planetary exploration rovers. Rovers undertaking planetary exploration require outstanding running performance to travel on loose ground on which they mostly
Tomohiro Watanabe, Kojiro Iizuka
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

GAS THRUST BEARING OF INCREASED BEARING CAPACITY WITH YIELDING BEARING SURFACE

Вестник Донского государственного технического университета, 2018
Basic operation factors of the deformed gas-lubricated thrust bearing with increased bearing capacity are theoretically analysed. It is shown that steady-state operation characteristics of this bearing differ from those of the rigid bearing.
Kamil S. AKHVERDIYEV, Murman A. MUKUTADZE, Vladimir A. KONSTANTINOV   +2 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

STUDY ON THE AXIAL BEARING CAPACITY OF T AEROSTATIC BEARING

Jixie qiangdu, 2016
Even a small axial vibration or an axis deflection vibration of the aerostatic bearing of DFC tool can be quite significant for ultra-precision machining. It is of great importance to obtain the accurate axial bearing characteristic（ bearing capacity and
ZHAO Gong, WANG BaoRui, YANG Hong, CUI HaiLong   +3 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Study on constant-resistance energy-absorbing components of hydraulic support for rock burst roadway and their anti-impact performance

Meitan kexue jishu
The significant fluctuation in bearing capacity remains a critical challenge to be addressed in thin-walled corrugated anti-impact energy-absorbing components.
Yimin SONG, Di WU, Dong AN, Hailiang XU, Tengteng WANG, Qiuliang WAN, Tian WEN, Jinying FAN   +7 more
doaj   +1 more source