Results 91 to 100 of about 317,209 (268)

Three-Dimensional Discrete Element Analysis of Bearing Characteristics of Concrete–Cored Sand–Gravel Pile Composite Foundation under Cyclic Dynamic Load

Buildings
Concrete-cored sand–gravel piles are a kind of composite pile formed by wrapping a concrete-cored pile with a sand–gravel shell, which has the advantages of both a rigid pile and bulk-material pile.
Binhui Ma, Wenbiao Tang, Tian Lan, Xu Deng, Bicheng Du   +4 more
doaj   +1 more source

Finite element simulation study on vertical bearing characteristics of single pile with ram-compacted bearing sphere. [PDF]

PLoS One, 2023
Bai L, Gong S, Xu L, Bai X, Huang Z.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Review of research progress on the theory and bearing characteristics of post-grouting for prestressed concrete pipe pile ends and sides

河南理工大学学报. 自然科学版
Significance Post-grouting of pipe piles is an effective technique for improving the physical and mechanical properties of the pile-soil interface， playing a significant role in enhancing the frictional resistance of pipe piles and reducing settlement of
HOU Zhenkun, CHEN Xuanlin, TANG Mengxiong, LING Zao, DU Xidong, XU Feng, HE Shaoyang, LIANG Shihua   +7 more
doaj   +1 more source

A case study on the bearing characteristics of a bottom uplift pile in a layered foundation. [PDF]

Sci Rep, 2022
He L, Chen X, Wang Z, Han Y, Su T, Dai G, Zhang E, Long Z.   +7 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The Transverse Bearing Characteristics of the Pile Foundation in a Calcareous Sand Area. [PDF]

Materials (Basel), 2022
Hu H, Luo L, Lei G, Guo J, He S, Hu X, Guo P, Gong X.   +7 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Study on time effect of residual pressure and bearing characteristics of jacked pile in saturated silt foundation. [PDF]

Sci Rep, 2022
Jiu YZ, Zhang XY, Zhu YZ, Zhang Z, Tian GH.   +4 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source