Results 91 to 100 of about 1,313,832 (317)

Simulation of non-linear bearing forces for post-stability investigation [PDF]

Different types of bearing designs were developed to improve dynamic properties of rotor-bearing systems. Elliptical bearings, multisleeve bearings, tilting pad and other designs such as herringbone groove were utilized to increase resistance to the ...
Krodiewski, J. M., Krynicki, K., Parszewski, Z. A., Salek, A. E.   +3 more
core   +1 more source

Determination of ball bearing dynamic stiffness [PDF]

, 1982
The dynamic radial stiffness characteristics of rolling element bearings are currently determined by analytical methods that have not been experimentally verified.
Beatty, R. F., Rowan, B. F.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Experimental Study on Bearing Characteristics of Pile-Anchor Foundations for Floating Offshore Wind Turbines Under Inclined Loading

Journal of Marine Science and Engineering
Pile-anchor foundations, serving as one of the anchoring solutions to ensure the safety and stability of floating offshore wind turbines, are primarily subjected to inclined loading induced by anchor chain forces, resulting in significantly different ...
Yuxuan Wang, Pingyu Liu, Bo Liu, Jiaqing Shu, Huiyuan Deng, Mingxing Zhu, Xiaojuan Li, Jie Chen, Haoran Ouyang   +8 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A novel continuously adjustable hydrodynamic bearing

, 1998
A novel form of adjustable fluid film bearing has been devised whereby the hydrodynamic conditions can be changed in a continuously controlled manner during operation. The principle can be applied to conventionally orientated journal bearings, i.e.
Martin, Keith, Parkins, David
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Comparative Experimental Study on Bearing Capacity of Roof Beneath Single Piles and Pile Groups in Karst Area

Buildings
By designing and conducting indoor model tests on single piles and 2 × 2 pile groups under four working conditions—underlying cave, overlying cave, pile penetrating underlying cave, and beaded caves—the failure mode of the roof was explored, and its ...
Xinquan Wang, Haitao Chen, Haibo Hu, Chen Liu, Yongle Tian, Jun Hong   +5 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Study on Load-Bearing Characteristics and Engineering Applications for Cement–Soil Pipe Pile

Buildings
The cement–soil pipe pile is a novel blend of cement and soil, designed to enhance load-bearing capabilities while cutting down on the need for cement. Its tubular construction is key to its strength.
Chong Zhou, Xiangzhuo Zheng, Sifeng Zhang, Chao Li, Yaohui Yang, Jianyong Han   +5 more
doaj   +1 more source