Results 51 to 60 of about 317,209 (268)
Management of Pile End Sediment and Its Influence on the Bearing Characteristics of Bored Pile
BuildingsIn order to study the influence of pile end sediment on the bearing characteristics of bored piles, the on-site bearing capacity test was conducted on a single pile.
Weibin Song +4 more
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Micromachines, 2020 Temperature rise and elastic deformation are unavoidable issues occurring in high-speed gas microbearings due to the dominant small-scale fluid dynamics in rarefied gas flow applications.
Yao Wu, Lihua Yang, Tengfei Xu, Wei Wu
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Numerical simulation of bearing mechanism of steel casing group in complex karst area
Carsologica SinicaThe construction of pile foundations in karst areas presents unique challenges due to the unpredictable spatial distribution of underground cavities, which may significantly increase the associated risk of such projects. Karst topography is characterized
Hui GUO +6 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Carsologica SinicaDue to the highly undulating terrain, complex geological conditions, and the widespread distribution of karst topography developed with underground karst caves in Southwest China, the construction of bridges and tunnels will inevitably traverse areas ...
Guiqing ZHAO +5 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Study on Bearing Characteristics of the Splicing Joint of Angle Steel-double T-type Beam
工程科学与技术, 2017 :The splicing joint,as an important connection part of steel truss,its bearing capacity and stiffness are important factors on safety and stability of steel truss.Based on the design of large-diameter silo construction support platform,two types of the ...
XIA Junwu +5 more
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