Results 21 to 30 of about 62,296 (265)

Silymarin Alleviates Oxidative Stress and Inflammation Induced by UV and Air Pollution in Human Epidermis and Activates β-Endorphin Release through Cannabinoid Receptor Type 2

Cosmetics
Background: Skin is exposed to ultraviolet radiation (UV) and air pollution, and recent works have demonstrated that these factors have additive effects in the disturbance of skin homeostasis.
Cloé Boira, Emilie Chapuis, Amandine Scandolera, Romain Reynaud   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Assessment of dermal fiber changes associated with age ethnicity and cosmetic product use by LC-OCT and automated 3D segmentation

Scientific Reports
This work presents a novel, non-invasive method that combines high-resolution 3D Line-field Confocal Optical Coherence Tomography (LC-OCT) images with an advanced, in-house developed automated 3D segmentation algorithm to quantitatively analyze dermal ...
Kamilia Kemel, Randa Jdid, Julie Latreille, Oriane Tarby, Lucas Gandel, Severine Ponsero, Nada André, Gabriel Cazorla, Youcef Ben Khalifa   +8 more
doaj   +1 more source

Age-dependent efficacy of transconjunctival lower eyelid fat removal: receiver operating characteristic curve-derived thresholds and multimodal recommendations [PDF]

Archives of Aesthetic Plastic Surgery
Background Transconjunctival lower eyelid fat removal is widely performed in Asian aesthetic practice, yet the domain-specific outcomes and the effects of age or adjunctive procedures remain unclear.
Keisuke Matsumura, Yuichi Jono, Hiromichi Okuma, Takahiko Tamura, Hiroo Teranishi   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The Natural Centella asiatica Extract Acts as a Stretch Mark Eraser: A Biological Evaluation

Cosmetics
Stretch marks are far from exclusively appearing on pregnant women and appear whenever the body experiences rapid growth. Collagen fibres are altered in the dermis, which is associated with a loss of orientation, and the elastic network is disrupted ...
Cloé Boira, Marie Meunier, Marine Bracq, Amandine Scandolera, Romain Reynaud   +4 more
doaj   +1 more source

Thinging Beauty. Anthropological Reflections on the Making of Beauty and the Beauty of Making

Reti, saperi, linguaggi, 2020
What does it mean to create a beautiful thing? What is the beauty of making? This paper explores the process of affective attunement by which selected aspects of the world come to matter to our senses and acquire aesthetic agency (the ability to move us). Aesthetic consciousness (experience and judgement) is the product of that process.
Malafouris, L, Koukouti, MD
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Anti-inflammatory effect of taxifolin in TNF-α/IL-17A/IFN-γ induced HaCaT human keratinocytes

Applied Biological Chemistry, 2023
Taxifolin, a bioactive flavonoid, has been attracting attention as a beneficial and valuable phytochemical due to its antioxidant, anticancer, and anti-inflammatory properties.
Jung Eun Park, Hee Jun Kwon, Hwa Jin Lee, Hyung Seo Hwang   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source