Results 31 to 40 of about 250,541 (308)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Inertia, Optimism and Beauty [PDF]
The best arguments for the 1/3 answer to the Sleeping Beauty problem all require that when Beauty awakes on Monday she should be uncertain what day it is.
Patrick Hawley, Hawley, Patrick
core
Heavy metals in particulate matter (PM) contribute to oxidative stress, DNA damage, and inflammatory responses in skin cells. This study aimed to investigate the toxic effects of airborne heavy metals on human sebocytes, keratinocytes, and ex vivo skin ...
Hye-Won Na +5 more
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Independent Repeated Sleeping Beauty [PDF]
In this paper, I shall provide a simple argument for the thirder analysis of the usual version of Sleeping Beauty\c and the hslfer analysis of a bare-bones version of the scenario.
Shulman, David
core
Background: Skin is exposed to ultraviolet radiation (UV) and air pollution, and recent works have demonstrated that these factors have additive effects in the disturbance of skin homeostasis.
Cloé Boira +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
This work presents a novel, non-invasive method that combines high-resolution 3D Line-field Confocal Optical Coherence Tomography (LC-OCT) images with an advanced, in-house developed automated 3D segmentation algorithm to quantitatively analyze dermal ...
Kamilia Kemel +8 more
doaj +1 more source
Thinging Beauty. Anthropological Reflections on the Making of Beauty and the Beauty of Making
What does it mean to create a beautiful thing? What is the beauty of making? This paper explores the process of affective attunement by which selected aspects of the world come to matter to our senses and acquire aesthetic agency (the ability to move us). Aesthetic consciousness (experience and judgement) is the product of that process.
Malafouris, L, Koukouti, MD
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

