Results 41 to 50 of about 185,293 (312)

Sleeping Beauty in Quantumland [PDF]

, 2001
It is argued that thirder resolution of the Lewis - Elga controversy about Sleeping Beauty is more clear when the coin toss is replaced by a quantum measurement and the analysis is performed in the framework of the Many-Worlds ...
Vaidman, Lev
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Natural dual inhibitor isorhamnetin-3-O-neohespeidoside targets tyrosinase and MC1R for skin pigmentation management

Scientific Reports
Skin pigmentation disorders involve complex biological regulation, with tyrosinase (TYR) and melanocortin 1 receptor (MC1R) serving as key therapeutic targets.
Rongrong Deng, Shiqian Zheng, Shengjun Xie, Gengjiu Huang, Zhiwen Ou, Zhibin Shen   +5 more
doaj   +1 more source

Investigation of Patients’ Motivation for Cosmetic Surgery in a Nationwide Cosmetic Surgery Group

Plastic and Reconstructive Surgery, Global Open
Background:. Recently, cosmetic surgeons in Japan have used social media to advertise their procedures. We analyzed the influence of social and other media on patients’ motivation to visit our clinic using the aggregated results of a questionnaire ...
Yusuke Funakoshi, MD, PhD, Masao Saito, MD, PhD, Ko Kawaguchi, MD, Eri Hiramatsu, MD, Nobuo Yamamoto, MD, Yoshiko Hondo, MD, Yumiko Nakagawa, MD, PhD, Koki Okumura, MD, Asami Sato, MD, Hiroo Teranishi, MD   +9 more
doaj   +1 more source

Thinging Beauty. Anthropological Reflections on the Making of Beauty and the Beauty of Making

Reti, saperi, linguaggi, 2020
What does it mean to create a beautiful thing? What is the beauty of making? This paper explores the process of affective attunement by which selected aspects of the world come to matter to our senses and acquire aesthetic agency (the ability to move us). Aesthetic consciousness (experience and judgement) is the product of that process.
Malafouris, L, Koukouti, MD
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

On the mathematics of beauty: beautiful music

CoRR, 2017
arXiv admin note: substantial text overlap with arXiv:1705 ...
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Perancangan Rangkaian Terpadu Penguat Operasional Untuk Pengatur Nada

Jurnal EECCIS (Electrics, Electronics, Communications, Controls, Informatics, Systems), 2012
Suatu rangkaian terpadu (integrated circuit -IC) adalah sebuah kristal silikon kecil yang disebut chip mengandung komponen elektronika seperti transistor,dioda, resistor, dan kapasitor. Komponen itu saling dihubungkan dalam chip membentuk suatu rangkaian
Beauty Beauty, Agung Darmawansyah, M. Julius Setyopranoto   +2 more
doaj   +1 more source