Results 171 to 180 of about 46,670 (237)
Cell Proliferation, Volume 59, Issue 2, February 2026.Mitochondrial quality control (MQC) impairment plays a central role in driving the pathogenesis of metabolism‐associated steatotic liver disease (MASLD). Specifically, this is manifested as reduced mitophagy; increased mitochondrial fission and decreased fusion; and impaired mitochondrial biogenesis.
Wenkai Fu +8 more
wiley +1 more source
PREP-modifikaatioiden vaikutus autofagiaan [PDF]
, 2017 Autophagy is a pathway for cells to degrade intracellular components that are no longer needed or are detrimental for the cells. It is essential for cell homeostasis and survival and has been related to various diseases and pathophysiology.
Huovila, Tiina
core
Glutamate Delta 1 Receptor in Synapses, Circuits, and Disease
European Journal of Neuroscience, Volume 63, Issue 3, February 2026.This review discusses our current understanding of the structure–function, expression and roles in neural circuits of the less studied glutamate delta 1 (GluD1) receptor. Converging data suggests many unique features of GluD1 including expression at both excitatory and inhibitory synapses and binding to D‐serine and GABA.
Diane Choi +3 more
wiley +1 more source
Exosomes in Hypertrophic Scars and Keloids: Mechanisms and Therapeutic Potentials—A Narrative Review
Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.ABSTRACT Background Hypertrophic scars and keloids, types of pathological scars, arise from dysregulated wound healing, marked by abnormal fibroblast activation and excessive extracellular matrix (ECM) deposition. Current treatments have high recurrence rates and side effects, necessitating targeted therapies. Exosomes, extracellular vesicles mediating
Mengke Wu +6 more
wiley +1 more source
Iranian Journal of Reproductive Medicine, 2015 Background: The pathogenesis of Gestational Trophoblastic Disease (GTD) is not clearly known. Objective: In this study, immunoexpression of proteins Bcl-2 and Beclin-1 in trophoblastic lesions and normal trophoblastic tissue was conducted to study the ...
Teresa Liliana Wargasetia +4 more
doaj
Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides. [PDF]
, 2019 Despite significant advances in the treatment of human immunodeficiency virus type-1 (HIV) infection, antiretroviral therapy only suppresses viral replication but is unable to eliminate infection. Thus, discontinuation of antiretrovirals results in viral
Campbell, Grant R +6 more
core
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.Liraglutide inhibits chronic stress‐induced vascular injury in mice by inhibiting the activation of the PI3K‐mTOR signaling pathway and promoting autophagy of smooth muscle cells or macroautophagy. ABSTRACT Chronic stress is a significant risk factor for postoperative restenosis and other cardiovascular diseases, as it can promote the intimal ...
Zongyi Zhang +14 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.This study reveals that the long non‐coding RNA DANCR drives pathological retinal neovascularization in oxygen‐induced retinopathy via an ANXA2‐dependent p38/MAPK/mTOR autophagy pathway. In hypoxic endothelial cells and a murine OIR model, DANCR promotes angiogenesis.
Yini Wang, Jiale Bai, Shihong Zhao
wiley +1 more source
Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats [PDF]
, 2018 Bové +42 more
core +2 more sources