Results 181 to 190 of about 30,020,506 (258)

Traditional Chinese Medicine Formulas in Delaying Aging: From Theoretical Foundations to Molecular Mechanisms and Translational Perspectives

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Aging is a systemic decline in physiological integrity, driving chronic diseases such as neurodegeneration, cardiovascular disorders, and metabolic syndromes. Rapid global population aging urgently demands effective interventions. Traditional Chinese medicine (TCM) formulas, characterized by multi‐component, multi‐target, and multi‐pathway ...
Chenrong Jin, Ding Du, Xiaorui Yu, Xiaoyan Ji, Xiuyun Zhang, Anning Li, Shuang Zu, Bo Qu, Daqing Zhao, Dianpeng Wu, Meichen Liu   +10 more
wiley   +1 more source

Differential Protective Actions of Dulaglutide and Dexamethasone in Methotrexate Induced Pulmonary Fibrosis: Relationship with AMPK and Beclin-1 Levels. [PDF]

Biomedicines
Maher OW, El-Sayed NM, El-Awady EE, El-Orabi NF, Radwan A.   +4 more
europepmc   +1 more source

Sirtuin signalling governs calcium homeostasis and mitochondrial function in metabolic syndrome cardiomyocytes

Experimental Physiology, Volume 111, Issue 10, Page 4646-4658, 1 October 2026.
Abstract Metabolic syndrome (MetS) is a major contributor to cardiovascular disease and is characterized by impaired Ca2+ handling and mitochondrial dysfunction in cardiomyocytes. However, the upstream mechanisms linking metabolic stress to these alterations remain incompletely defined.
Firat Akat, Leila Aryan, Suatnur Şık, Erkan Tuncay   +3 more
wiley   +1 more source

Desmoplakin Mutations in Cardiac Fibroblasts Cause TGFβ1-Mediated Pathological Fibrogenesis in Desmoplakin Cardiomyopathy Via Beclin-1 Regulation. [PDF]

Circ Res
Wei C, Shou W, Chan SF, Saguner AM, Brunckhorst C, Duru F, Marine JE, James CA, Calkins H, Judge DP, Chen HV.   +10 more
europepmc   +1 more source

Beclin 1 level combined with Gensini score and low-density lipoprotein cholesterol correlate strongly with multi-vessel disease. [PDF]

Am J Transl Res
Qu Y, Xue Y, Xiong X, Jia J, Xie Y, Li H, Sun J, Liu Q, Chen B.   +8 more
europepmc   +1 more source

Electroacupuncture Ameliorates Premature Ovarian Insufficiency by Inhibiting METTL3-Mediated m6A Methylation of Beclin 1 mRNA in Granulosa Cells. [PDF]

Food Sci Nutr
Ling L, He S, Zhao X, Sheng Y, Hong M, Yuan L, Liu P, Ke B, Li B, Zhang B.   +9 more
europepmc   +1 more source

The Biological Role and Clinical Significance of BECLIN-1 in Cancer. [PDF]

Int J Mol Sci
Maheshwari C, Castiglioni A, Walusimbi U, Vidoni C, Ferraresi A, Dhanasekaran DN, Isidoro C.   +6 more
europepmc   +1 more source

Stanniocalcin 2-Induced Autophagy Confers Resistance of Lung Cancer Cells to EGFR Inhibition via the ERK/Beclin 1 Signaling. [PDF]

Cancer Med
Liu YN, Chen YL, Tsai MF, Wu SG, Chang TH, Tsai TH, Shih JY.   +6 more
europepmc   +1 more source

[Expression of Concern] Valosin-containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF-κβ/beclin-1 signaling pathway. [PDF]

Oncol Lett
Long XH, Zhou YF, Lan M, Huang SH, Liu ZL, Shu Y.   +5 more
europepmc   +1 more source

Epidermal growth factor receptor regulates Beclin-1 in hyperoxic acute lung injury. [PDF]

BMJ Open Respir Res
Harris ZM, Korde A, Khoury J, Manning EP, Stanley G, Shin Y, Mitchell K, von der Schulenburg A, Sun Y, Hu B, Shin HJ, Joerns J, Clark B, Placek L, Unutmaz D, Moldobaeva A, Sharma L, Sauler M, Rajagopalan G, Zhang X, Wang H, Ghaedi M, Kang MJ, Koff JL.   +23 more
europepmc   +1 more source