Results 91 to 100 of about 1,913,332 (299)
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Background Mental health problems (MHP) are a major public health challenge. Conventional healthcare has shown limitation on reducing MHP and there is a call for offering methods beyond healthcare as well as improve access to healthcare.Aims To explore ...
Inger Jansson +2 more
doaj +1 more source
O presente trabalho fala de um relato sobre os jovens pobres inscritos em uma experiência de formação profissional em uma unidade militar no Rio de Janeiro.
Eduardo Antonio de Pontes Costa +1 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Becoming Deterritorialized: Reading Tim Etchells’ The BRoKen WoRLD after Gilles Deleuze
The philosophy of Gilles Deleuze is a complex and open system whose “anything-goes” or, to borrow Deleuze’s own term, rhizomatic, i.e. interconnected and interconnectable nature constitutes a major potential of the theory for many areas of academic ...
Jan Suk
doaj
This article analyses artworks by three non-binary or trans masculine artists: Kris Grey, No title (2019), Emmett Ramstad, The good ones (2006), and Marie Ahlberg Andersen, My Dick Clit has many forms (2022).
Storm Madsen
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Episode 95: Becoming Bat with Angelica Caiza Villegas
In this episode of Knowing Animals I am joined by Angelica Caiza Villegas. Angelica is a PhD student in the Department of Cultural Geography at the University of Groningen in the Netherlands.
Villegas, Angelica Caiza +1 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Creative involution : overcoming man : becoming-woman [PDF]
The thesis is written in the pursuit of true difference. Its contention is that true difference has been obscured by a model of difference which is dialectical in nature.
Crawford, Jane-Ann
core

