Results 91 to 100 of about 4,848,339 (309)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Becoming a Seer: Thoughts on Deleuze, Mindfulness and Feminism [PDF]

open access: yes, 2017
This essay circles around two ideas. First, I try to answer the ethical question “What is the right thing to do?” through the application of the French philosopher Gilles Deleuze’s affirmative philosophy.
Janning, Finn
core  

Becoming “Holistically Indigenous”: Young Muslims and Political Participation in Canada [PDF]

open access: yes, 2013
While media and the government often focus on the supposed “radicalization” of Muslim youth in Canada, our research explores the more complicated and nuanced political identities among 20 young Canadian Muslims.
Bullock, Katherine   +1 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Judging the Risk of Becoming Infected through Sexual Encounters [PDF]

open access: yes, 2001
The authors examine the manner in which people integrate pieces of information to assess the risk of becoming infected through sexual ...
Arnaud, Simeone   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Alice au-delà du selfie. Pour être digne de ce qui lui arrive [PDF]

open access: yesLa Deleuziana, 2015
Alice’s becoming, as becoming simultaneously larger and smaller, provides the oppor-­‐‑ tunity to diagnose the present through a phenomenon more “current” than ever: Tiqqun’s “Jeune-­‐‑Fille” (young girl), which today is amplified by social networks.
Paolo Vignola
doaj  

Becoming Citizen: Spatial and Expressive Acts when Strangers Move In

open access: yesSocial Inclusion, 2018
This article examines the conditions and expressions of how refugees in Denmark become citizens. Through visual and collaborative ethnographic fieldwork, which took place during 2017, the case study follows the everyday life of an Eritrean community ...
Peter Kærgaard Andersen   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Beyond conventional healthcare for mental health problems: Experiences of existential group conversations

open access: yesScandinavian Journal of Occupational Therapy
Background Mental health problems (MHP) are a major public health challenge. Conventional healthcare has shown limitation on reducing MHP and there is a call for offering methods beyond healthcare as well as improve access to healthcare.Aims To explore ...
Inger Jansson   +2 more
doaj   +1 more source

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