Results 71 to 80 of about 1,913,332 (299)
Becoming, relativity and locality [PDF]
, 2005 It is a central aspect of our ordinary concept of time that history unfolds and events come into being. It is only natural to take this seriously. However, it is notoriously difficult to explain further what this `becoming' consists in, or even to show ...
Dieks, Dennis
core
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
, 2021 Mentors: Unnar Örn Jónasson Auðarson & Angela Rawlings Evaluators: Þorgerður E. Sigurðardóttir & Eva Rún SnorradóttirWhat we bring into becoming invites an audience to think about how monument and monumentality can be seen as unique and ever ...
Annie Charland Thibodeau 1990-
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
ON BECOMING, COSMIC TIME AND ROTATING UNIVERSES [PDF]
, 2001 In the literature on the compatibility between the time of our experience and the time of physics, the special theory of relativity has enjoyed central stage.
Dorato, Mauro
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Educar em Revista, 2011 Este artigo relata o processo de investigação para a construção e aplicação de um conjunto de atividades relacionadas à temática água, em um Colégio de Curitiba.
Vandamir Palmeiro, Christiane Gioppo
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source