Results 81 to 90 of about 1,913,332 (299)

Structura și analiza literară a prologului ioanin

open access: yesTheoRhēma, 2019
The prologue of the Gospel of John should be seen as one of the most difficult biblical passages to interpret due to its hymnic structure. Many researchers have tried to grasp its core and to understand its background and purpose.
Marius Mitrache
doaj  

La ciudad Islámica: una interpretación femenina = The Islamic city: A female interpretation

open access: yesTerritorios en Formación, 2019
Resumen Agar, la concubina de Abraham y la madre de la nación árabe, es la fundadora de la ciudad islámica, Meca. En la mitología islámica Agar, una vez expulsada de la tienda de Abraham y Sara, vaga desesperadamente por el desierto Paran, en busca de ...
Narges Bazarjani
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Becoming an Advocate [PDF]

open access: yesJournal of Investigative Dermatology, 2006
Specialization occurs as tasks and knowledge within a society become increasingly complex. We divide the tasks into units manageable by individuals or specially trained groups. As a society, we invest resources to train individuals in specific tasks and skill sets and to teach them to acquire and disseminate knowledge.
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A song to Sana in (becoming) sea

open access: yes, 2023
A song to Sana in (becoming) sea is a love letter to my unborn son. As a piece that works through grief, it recognises that grief as embodiment is a series of processes of accumulation, as well as of weaving and attuning to multiple human and more-than ...
Mejia Moreno, Catalina
core   +2 more sources

Becoming Citizen: Spatial and Expressive Acts when Strangers Move In

open access: yesSocial Inclusion, 2018
This article examines the conditions and expressions of how refugees in Denmark become citizens. Through visual and collaborative ethnographic fieldwork, which took place during 2017, the case study follows the everyday life of an Eritrean community ...
Peter Kærgaard Andersen   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Alice au-delà du selfie. Pour être digne de ce qui lui arrive [PDF]

open access: yesLa Deleuziana, 2015
Alice’s becoming, as becoming simultaneously larger and smaller, provides the oppor-­‐‑ tunity to diagnose the present through a phenomenon more “current” than ever: Tiqqun’s “Jeune-­‐‑Fille” (young girl), which today is amplified by social networks.
Paolo Vignola
doaj  

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