Results 181 to 190 of about 155,817 (261)

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Erratum: Extensive dynamic changes in the human transcriptome and its circadian organization during prolonged bed rest. [PDF]

iScience
Archer SN, Möller-Levet C, Bonmatí-Carrión MÁ, Laing EE, Dijk DJ.   +4 more
europepmc   +1 more source

In‐Process Magnetization for 3D Printing of Magnetorheological Elastomer with Heterogeneous Magnetic Profile for Anisotropic Actuation

Advanced Science, EarlyView.
Fully programmable, in‐process 3D magnetization integrated with multi‐material printing enables soft magnetic systems with precise actuation and sensing. Discrete and continuous magnetization profiles drive bending, morphing, and locomotion, demonstrated through strain‐sensing elements, dragonfly‐inspired wings, octopus‐like tentacles, and a serpentine
Phillip Glass, David Hassouna, Udena Epitawala Arachchige, Hyeon Yun Jeong, Sung Hyun Park, Daeha Joung   +5 more
wiley   +1 more source

Bed-rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism. [PDF]

J Cachexia Sarcopenia Muscle
Shur NF, Simpson EJ, Crossland H, Constantin D, Cordon SM, Constantin-Teodosiu D, Stephens FB, Brook MS, Atherton PJ, Smith K, Wilkinson DJ, Mougin OE, Bradley C, Macdonald IA, Greenhaff PL.   +14 more
europepmc   +1 more source

Learning Moisture‐Induced Damage From Vision: Diffusion Models for Real‐Time Monitoring of Additive Manufacturing Processes

Advanced Science, EarlyView.
We introduce a vision‐based real‐time monitoring system for additive manufacturing that detects subtle moisture‐induced degradation via a diffusion model‐based framework. The approach enables nondestructive assessment of moisture‐induced damage level and mechanical performance and establishes a practical route toward more intelligent, reliable, and ...
Jiyoung Jung, Yuna Yoo, Dharneedar Ravichandran, Dahyun Daniel Lim, Grace X. Gu   +4 more
wiley   +1 more source

Exceptional CO2 Hydrogenation to Gasoline Enabled by GaZrOx/Ga‐ZSM‐5 Tandem Catalyst

Advanced Science, EarlyView.
A GaZrOx/Ga‐ZSM‐5 tandem catalyst achieves 17.2% CO2 conversion with 83.2% C5+ selectivity and >400 h stability relies on optimized O‐vacancies and Ga‐H coverage for CO2 hydrogenation. ABSTRACT CO2 hydrogenation to gasoline offers a promising route for addressing energy challenges and enabling the effective utilization of carbon resources. However, the
Wenhui Li, Yujing Sun, Bingyu Liu, Yaoyang Ni, Hong Yang, Xinwen Guo   +5 more
wiley   +1 more source

Skeletal muscle properties in long COVID and ME/CFS differ from those induced by bed rest

Charlton BT, Slaghekke A, Appelman B, Eggelbusch M, Huijts JY, Noort W, Hendrickse PW, Bloemers FW, Posthuma JJ, van Amstel P, Goulding RP, Degens H, Jaspers RT, van Vugt M, Wüst RC.   +14 more
europepmc   +1 more source

Mechanical countermeasures for spaceflight-associated neuro-ocular syndrome during 30-days of head down tilt bed rest: design, implementation, and tolerability. [PDF]

Front Physiol
Moestl S, De Boni L, Hoenemann JN, Kramer T, Schmitz J, Pesta D, Frett T, Bohmeier M, Frings-Meuthen P, Ewald AC, Nitsche A, Loehr P, Noppe A, Klischies N, Huang AS, Laurie SS, Marshall-Goebel K, Macias BR, Tank J, Jordan J, Mulder E.   +20 more
europepmc   +1 more source

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Role of ultrasonography in assessing respiratory muscle loss: insights from a cross-sectional study on neurological patients with long-term bed rest with and without tracheostomy. [PDF]

BMC Pulm Med
Dong J, Xie Z, Wang W, Li Y, Li S, Zhang F, Jin L.   +6 more
europepmc   +1 more source