Pharmacological Alternatives for the Treatment of Neurodegenerative Disorders: Wasp and Bee Venoms and Their Components as New Neuroactive Tools [PDF]
Toxins, 2015 Neurodegenerative diseases are relentlessly progressive, severely impacting affected patients, families and society as a whole. Increased life expectancy has made these diseases more common worldwide.
Juliana Silva +11 more
doaj +3 more sources
Assessing the Utility of Broad-Acting Inhibitors as Therapeutics in Diverse Venoms [PDF]
ToxinsExamination of venom constituent bioactivities from diverse venomous animals shows certain highly conserved classes, including enzymes (e.g., phospholipases and metalloproteinases) and pore-forming proteins.
Raechel Kadler +2 more
doaj +4 more sources
Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan [PDF]
Toxins, 2015 While knowledge of the composition and mode of action of bee and wasp venoms dates back 50 years, the therapeutic value of these toxins remains relatively unexploded.
Miguel Moreno, Ernest Giralt
doaj +2 more sources
A Review on Genotoxic and Genoprotective Effects of Biologically Active Compounds of Animal Origin
Toxins, 2023 Envenomation by animal venoms remains a serious medical and social problem, especially in tropical countries. On the other hand, animal venoms are widely used as a source of biologically active compounds for the development of novel drugs.
Nikolajs Sjakste, Goran Gajski
doaj +2 more sources
Antimicrobial and antibiofilm effects of melittin and apamin bee venoms from apis mellifera l. on eskape pathogens and cytotoxic effects on l929 fibroblast cells [PDF]
Kafkas Universitesi Veteriner Fakültesi DergisiPublic health is facing a worldwide challenge due to the emergence of multiple antibiotic resistance in ESKAPE (Enterococcus faecalis, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Escherichia coli ...
Elif AYDIN +3 more
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Secreted Phospholipases A2 from Animal Venoms in Pain and Analgesia
Toxins, 2017 Animal venoms comprise a complex mixture of components that affect several biological systems. Based on the high selectivity for their molecular targets, these components are also a rich source of potential therapeutic agents.
Vanessa O. Zambelli +4 more
doaj +2 more sources
Differentiation Between Natural and Commercial Bee Venoms Using Fluorescence Spectroscopy
To Chemistry Journal, 2018 Honey bee venom (HBV, A. m. scutellata) contains polypeptides [melittin, mast cell degranulating peptide (MCD), adolapin and apamin] and enzymes.The aim of the present study was to differentiate between commercial and natural bee venoms using aqueous ...
Abdul Mosbah Gbaj
doaj +4 more sources
Interaction of Human Lymphocyte Scavenger Receptors CD5 and CD6 with Toxins from Naja haje, Androctonus australis and Apis mellifera Venoms [PDF]
BiomoleculesAnimal venoms induce systemic inflammatory response syndrome through their interaction, inter alia, with pattern recognition receptors (PRRs) of the innate immune system.
Dalila Khemili +9 more
doaj +2 more sources
Bee Venom Acupuncture for Shoulder Pain: A Literature Review of Clinical Studies
ToxinsManaging shoulder pain typically involves the use of acetaminophen or oral nonsteroidal anti-inflammatory drugs, but prolonged use of these medications can lead to dependence and various side effects.
Hyein Jeong +6 more
doaj +2 more sources
BMC Infectious Diseases, 2006 Background Burkholderia pseudomallei are the causative agent of melioidosis. Increasing resistance of the disease to antibiotics is a severe problem in treatment regime and has led to intensification of the search for new drugs.
Chow Vincent TK +7 more
doaj +2 more sources