Results 61 to 70 of about 13,597,255 (340)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Activity-informed Dynamic Data Driven Simulation

open access: yesITM Web of Conferences, 2013
In previous work we developed dynamic data driven simulation (DDDS) that assimilates real time sensor data using Sequential Monte Carlo (SMC) methods.
Hu Xiaolin, Rai Sanish, Wang Xiaoming
doaj   +1 more source

Numerical simulation of single bubble boiling behavior

open access: yesPropulsion and Power Research, 2017
The phenomena of a single bubble boiling process are studied with numerical modeling. The mass, momentum, energy and level set equations are solved using COMSOL multi-physics software.
Junjie Liu   +5 more
doaj   +1 more source

Simulation of liquid fuel combustion start-up dynamical behavior

open access: yesCase Studies in Thermal Engineering, 2021
A successful ignition is the consequence of corresponding conditions of fuel mass flow rates, mixture ratio, as well as initiation energy in time and space.
Mukkarum Hussain   +6 more
doaj   +1 more source

Computer Simulation of Oscillatory Behavior in Cerebral Cortical Networks [PDF]

open access: yes, 1990
It has been known for many years that specific regions of the working cerebral cortex display periodic variations in correlated cellular activity. While the olfactory system has been the focus of much of this work, similar behavior has recently been ...
Bower, James M., Wilson, Matthew A.
core  

Critical behavior in colloid-polymer mixtures: theory and simulation

open access: yes, 2006
We extensively investigated the critical behavior of mixtures of colloids and polymers via the two-component Asakura-Oosawa model and its reduction to a one-component colloidal fluid using accurate theoretical and simulation techniques. In particular the
D. Frenkel   +13 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Study on Vacuum Breakdown Properties of Surface-Modified 304 Stainless Steel Electrodes Based on Fractal Theory

open access: yesNanomaterials
This paper reports on the effect of the micro-morphological characteristics of stainless steel electrodes on vacuum breakdown properties under the action of a strong electric field generated by high-power electric pulses.
Shiqing Wang   +6 more
doaj   +1 more source

Atomistic simulation of the diffusion behavior in Al-Fe

open access: yesNuclear Materials and Energy, 2021
The diffusion behavior of the Al-Fe system was investigated by a classical molecular dynamics simulation for simulating the Al coating process on Fe. Two bulks were built as the model: one bulk contained Al atoms and the other was made from Fe atoms. The
Junaidi Syarif   +2 more
doaj   +1 more source

Robust Simulation for Hybrid Systems: Chattering Path Avoidance [PDF]

open access: yes, 2015
The sliding mode approach is recognized as an efficient tool for treating the chattering behavior in hybrid systems. However, the amplitude of chattering, by its nature, is proportional to magnitude of discontinuous control.
Aljarbouh, Ayman, Caillaud, Benoit
core   +5 more sources

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