Results 71 to 80 of about 13,597,255 (340)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Artificial Taste: Advances and Innovative Applications in Healthcare

open access: yesApplied Sciences
Background: Scientists have recently developed a technology that induces artificial taste through electronic stimulation. However, scattered reports have made it difficult to comprehensively understand the technology’s details and appreciate its ...
Letao Wang   +3 more
doaj   +1 more source

Power-Law Distributions in Circulating Money: Effect of Preferential Behavior

open access: yes, 2005
We introduce preferential behavior into the study on statistical mechanics of money circulation. The computer simulation results show that the preferential behavior can lead to power laws on distributions over both holding time and amount of money held ...
Ding N.   +8 more
core   +1 more source

Behavior, Sensitivity, and power of activation likelihood estimation characterized by massive empirical simulation

open access: yesNeuroImage, 2016
Given the increasing number of neuroimaging publications, the automated knowledge extraction on brain-behavior associations by quantitative meta-analyses has become a highly important and rapidly growing field of research.
S. Eickhoff   +7 more
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deformation behavior of single-crystal magnesium during Nano-ECAP simulation

open access: yesHeliyon, 2022
Molecular dynamics was applied to simulate ECAP of single-crystal magnesium at room temperature. Four samples with different orientations were processed, and the grain structure, grain fragmentation, slip systems, strain, and twin formation were analyzed.
Amro H. Altoyuri   +2 more
doaj   +1 more source

Critical Behavior at the Chiral Phase Transition [PDF]

open access: yes, 1997
Quantum chromodynamics with two zero mass flavors is expected to exhibit a phase transition with O(4) critical behavior. Fixing the universality class is important for phenomenology and for facilitating the extrapolation of simulation data to physical ...
Amit   +18 more
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Phase coexistence of cluster crystals: beyond the Gibbs phase rule

open access: yes, 2007
We report a study of the phase behavior of multiple-occupancy crystals through simulation. We argue that in order to reproduce the equilibrium behavior of such crystals it is essential to treat the number of lattice sites as a constraining thermodynamic ...
B. M. Mladek   +8 more
core   +2 more sources

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