Results 101 to 110 of about 11,348,603 (380)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Behavior Modification

open access: yes, 1999
Excerpt: Behavior modification is learning with a particular intent, namely clinical treatment and change (Ullmann & Krasner, 1965, p. 1). Initially behavior modification referred largely to operant techniques and behavior therapy to respondent ...
Bufford, Rodger K.
core  

Heating and Cooling Dynamics of Carbon Nanotubes Observed by Temperature-Jump Spectroscopy and Electron Microscopy [PDF]

open access: yes, 2009
Microscopy imaging indicates that in situ carbon nanotubes (CNTs) irradiation with relatively low dosages of infrared radiation results in significant heating of the tubes to temperatures above 1300 K.
Mohammed, Omar F.   +2 more
core   +1 more source

DRA dengan Token Ekonomi untuk Menurunkan Perilaku Makan yang Menyimpang: Sebuah Studi Kasus pada Anak

open access: yesGadjah Mada Journal of Professional Psychology
Children of homeless people often experience various issues, one of which is eating behavior problems. Eating food from trash cans is a common eating behavior problem encountered. Therefore, an intervention is needed to reduce this issue. This case study
Smita Dinakaramani
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Cognitive Behavior Therapy

open access: yesMedical Journal of Dr. D.Y. Patil University, 2013
Cognitive behavior therapy (CBT) theorists propose that disturbances in cognition underlie and maintain much emotional disturbance. Accordingly the cognitive addition to behavioral therapy typically consists in collaboratively noticing, restructuring, de-fusing from, and challenging these cognitions by the therapist and the patient.
Daniel Saldanha   +3 more
openaire   +4 more sources

Acceptance and Commitment Therapy for Health Behavior Change: A Contextually-Driven Approach

open access: yesFrontiers in Psychology, 2018
Promoting health behavior change presents an important challenge to theory and research in the field of health psychology. In this paper, we introduce a context-driven approach, the Acceptance and Commitment Therapy (ACT) model which is built on ...
Chunqing Zhang   +5 more
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Effective Interventions for Treating Superficial Self Mutilators [PDF]

open access: yes, 2008
Self-cutting is the most common form of self-mutilation in adolescents but there is insufficient knowledge as to which treatment methods to reduce self-mutilation are most effective.
Palladini, Maria
core   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

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