Results 141 to 150 of about 11,021,950 (406)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

ISLAMIC PSYCHOLOGY IN TREATING VICTIMS OF CHILD SEXUAL ABUSE (Family Therapy and Story Telling Therapy) IN TREATING VICTIMS OF CHILD SEXUAL ABUSE [PDF]

open access: yes, 2016
The purpose of this study was to describe the changes experienced by the subjects after family therapy and storytelling therapy. This research used descriptive qualitative study with Curative Therapy methods and the Observational Analysis.
Desiningrum, Dinie Ratri
core  

A Computational Framework for Behavioral Assessment of LLM Therapists [PDF]

open access: yesarXiv
The emergence of large language models (LLMs) like ChatGPT has increased interest in their use as therapists to address mental health challenges and the widespread lack of access to care. However, experts have emphasized the critical need for systematic evaluation of LLM-based mental health interventions to accurately assess their capabilities and ...
arxiv  

Genomic landscape and preclinical models of angiosarcoma

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 965-983, April 2025.
Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton   +3 more
wiley   +1 more source

Behavioral Interventions as an Adjunctive Treatment for Canine Epilepsy: A Missing Part of the Epilepsy Management Toolkit?

open access: yesFrontiers in Veterinary Science, 2019
Epilepsy is a common, complex and often challenging neurological disorder to treat in the dog, with 20–30% of dogs resistant to conventional medical therapies, and associated with cognitive and behavioral comorbidities and early death.
Rowena M. A. Packer   +2 more
doaj   +1 more source

Misusing Freud: Psychoanalysis and the Rise of Homosexual Conversion Therapy

open access: yes, 2014
Current ideas of conversion therapy often focus on extremist religious groups that wish to cleanse the world of what they view as an immoral abomination, homosexuality. However, conversion therapy started out as mostly scientific curiosity. Sigmund Freud’
Barrett, Jonathan
core  

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1386-1403, May 2025.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

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