Results 141 to 150 of about 11,348,603 (380)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Behavior Therapy in the Era of Diagnostic Categories. [PDF]
, 1996 William C. Follette
openalex +1 more source
Group Counseling Management Based On Cognitive Behavior Therapy For Mental Retarded Students (A Site Study at SMPLB Bina Putera Ambarawa, Semarang) [PDF]
, 2012 Focus of this study is on the characteristics of group counseling based on cognitive behavior therapy at SMPLB (Special Secondary School) Bina Putera Ambarawa, Semarang. This study has three objectives.
Sulistyowati, Sulistyowati
core
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Efektivitas Cognitive Behavior Therapy Untuk Menurunkan Kecemasan Berbicara Di Depan Umum Pada Mahasiwa [PDF]
, 2017 Kompetensi mahasiswa dalam berbicara di depan umum dalam lingkup akademis telah menjadi tuntutan yang sewajarnya guna menyiapkan mahasiswa memiliki daya saing yang tinggi dan sebagai bekal kehidupan bermasyarakat.
Fitri, D. (Dian)
core +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
‘Quality of life’ after therapy in rats with myocardial infarction: dissociation between hemodynamic and behavioral improvement [PDF]
, 1996 Regien G. Schoemaker +2 more
openalex +1 more source
The effect of dialectical behavior therapy on executive function in patients with a bipolar disorder [PDF]
, 2018 Background: Bipolar disorder is a debilitating psychiatric disorder characterized by recurrent depression, manic and hippomanic episodes. The effect of a dialectical behavior therapy on executive functions in bipolar disorders has not been addressed so ...
Afshari, Behrooz +2 more
core
Case Report of Writers Cramp Syndrome Along with Myoclonic Epilepsy and Compulsion
پزشکی بالینی ابن سینا, 2009 Introduction: The writer's cramp syndrome is a kind of local dystonia which appears in the hands due to uncontrollable muscular spasms, making a hard and tiring job of writing for patients.
Alireza Moghaddas, Mitra Nasseri
doaj
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source