Results 101 to 110 of about 2,827,572 (302)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Other title: Annual Reports from Subcommittees of the Governor's Behavioral Health Services Planning Council

open access: yes, 2013
application/pdf; Includes bibliographical references (page [44 of 71]).A set of 9 Annual Reports from Subcommittees of the Governor's Behavioral Health Services Planning Council, and 1 summary.Aging Subcommittee Report 2013 (July 10, 2013).
Kansas. Governor's Behavioral Health Services Planning Council.
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Behaviorism and the stages of scientific activity [PDF]

open access: yesThe Behavior Analyst, 2010
Following from an earlier analysis by B. F. Skinner, the present article suggests that the verbal processes in science may usefully be viewed as following a three-stage progression. This progression starts with (a) identification of basic data, then moves to (b) description of relations among those data, and ultimately concludes with (c) the deployment
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Behavioral Activation Links to Creativity Because of Increased Cognitive Flexibility

open access: yes, 2010
Previous work suggests that trait behavioral activation may link to creativity, a possibility the authors empirically examine in this article. This research is grounded in the dual pathway to creativity model and experiments on approach orientation, and
Carsten K. W. De Dreu   +2 more
core   +2 more sources

Behavioral activation and behavioral inhibition sensitivities in patients with substance use disorders: A study from India

open access: yesIndian Journal of Psychiatry, 2018
Introduction: Addictive disorders are an epiphenomenon of underlying vulnerabilities. Research over the past decades into these vulnerabilities has distinguished internalizing and externalizing spectra as two distinct personality factors underlying ...
Suhas Ganesh   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Examining Motivational Systems (Behavioral Inhibition and Behavioral Activation) as Mediators between Decision Making and Impulsivity in ADHD

open access: yes, 2023
Some of the major hallmarks of attentional disorders include inappropriate decision making and unnecessary risk taking (Toplak, Jain, & Tannock, 2005).
Boldrini, Anthony   +3 more
core  

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