Results 111 to 120 of about 2,827,572 (302)

Effect of behavioral activation on self-compassion in mothers of children with autism in Babol, Iran: A randomized controlled trial [PDF]

Journal of Nursing Advances in Clinical Sciences
Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition that imposes significant psychological stress on parents, particularly mothers. Enhancing maternal psychological well-being through effective interventions is essential. This study
Zohreh Bigom Sefidgar, Ali Alvandi, Kimia Saeedi, Ailin Delavari, B Sunil S De Silva   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Behavioral activation for depressed patients in Iran: Effectiveness, predictors and mediators in the context of a randomized trial [PDF]

, 2015
Behavioral activation is a relatively new psychological treatment that could be a viable alternative and effective treatment for people with major depressive disorder.
Moradveisi, L., L. Moradveisi
core   +1 more source

Evaluating the necessity of booster sessions in relapse prevention for depression: a longitudinal study

Frontiers in Psychology
IntroductionMajor depression is a highly prevalent and heterogenous mental disorder. Although therapeutic advances for major depressive disorder over the past quarter-century have been incremental rather than transformative, booster sessions have been ...
Jón Ingi Hlynsson, Jón Ingi Hlynsson, Tómas Kristjánsson, Gerhard Andersson, Gerhard Andersson, Gerhard Andersson, Per Carlbring, Per Carlbring, the ACTUA research group   +8 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Annual report to the Behavioral Health Partnership Oversight Council. 2010: Dec.

, 2012
Annual; Began with 2009?; "Pursuant to CGS Section 17a-22m ..."--Letter of transmittal (publisher's Web site, viewed Apr. 1, 2011)
Connecticut Behavioral Health Partnership.
core   +1 more source

I-CONECT intervention effects on weekly time spent outside of home and social contacts among socially isolated older adults

Frontiers in Public Health
BackgroundSocially isolated individuals tend to have less access to cognitively stimulating activities, which could adversely impact their cognitive health.
Kexin Yu, Kexin Yu, Chao-Yi Wu, Lisa C. Silbert, Lisa C. Silbert, Jeffrey A. Kaye, Jeffrey A. Kaye, Hiroko H. Dodge   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Cognitive behavioral therapy for ADHD predominantly inattentive presentation: randomized controlled trial of two psychological treatments

Frontiers in Psychiatry
IntroductionAttention-Deficit Hyperactivity Disorder (ADHD) in adults is common and characterized by difficulties in regulation of attention, activity and goal directed behaviors.
Elinor Eskilsson Strålin, Lisa B. Thorell, Tobias Lundgren, Sven Bölte, Sven Bölte, Sven Bölte, Benjamin Bohman   +6 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source