Results 141 to 150 of about 284,523 (282)

Mobitz II atrioventricular block and CPAP response in a patient with severe obstructive sleep apnea, a case report

open access: yesSleep Science and Practice
Background At any stage during the sleep cycle, cardiac arrhythmia can happen. While many of these arrhythmias are benign, some of them are dangerous and may result in cardiovascular events that could be life-threatening.
Farkhondeh Nikkhah   +2 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Rationally Addicted to Cigarettes, Alcohol and Coffee? A Pseudo Panel Approach [PDF]

open access: yes
In this paper, using pseudo panel data we analyze the relation between cigarette, alcohol, and coffee consumption within the rational addiction framework. Our purpose in this study is twofold.
Koksal, Aycan, Wohlgenant, Michael K.
core   +1 more source

Considering Convergence: A Policy Dialogue About Behavioral Genetics, Neuroscience, and Law [PDF]

open access: yes, 2006
Garland and Frankel issue a call for scientists, lawyers, courts and lawmakers to begin a critical dialogue about the implications of scientific discoveries and technological advances in criminal law, behavioral genetics and ...
Frankel, Mark S., Garland, Brent
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Repetitive Transcranial Magnetic Stimulation (rTMS) as a Promising Treatment for Craving in Stimulant Drugs and Behavioral Addiction: A Meta-Analysis. [PDF]

open access: yesJ Clin Med, 2022
Gay A   +10 more
europepmc   +1 more source

HOURS OF GAMING OR NON-ACADEMIC COMPUTER USE, SUBSTANCE USE, MENTAL HEALTH STATUS AND SCHOOL PERFORMANCE AMONG TEXAS ADOLESCENCE: FINDINGS FROM THE 2017 YRBS IN TEXAS [PDF]

open access: yes, 2018
Online gaming activities among adolescents and adults has increased exponentially in the last decade, and mental health issues associated with excessive gaming have drawn attention from health care professionals worldwide (Griffith, 2016).
Gao, Shanxiazi
core   +1 more source

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