Results 141 to 150 of about 284,658 (331)

The Pitfalls of Recycling Substance-Use Disorder Criteria to Diagnose Behavioral Addictions

open access: green, 2022
Maèva Flayelle   +3 more
openalex   +2 more sources

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Treatment of Exercise Addiction: The current State of Knowledge

open access: yesQuality in Sport
Background: The concept of exercise addiction is commonly understood as a repetitive behavior involving compulsive physical activity despite negative physical, psychological, or social consequences.
Julia Janowiak   +9 more
doaj   +1 more source

Severity of behavioral addiction symptoms among young adults using non-prescribed sedatives/hypnotics. [PDF]

open access: yesAddict Behav Rep, 2023
Péter L   +8 more
europepmc   +1 more source

Internet addiction and loneliness among children and adolescents in the education setting: an empirical pilot study [PDF]

open access: yes, 2014
Research into various behavioural addictions has shown that such behaviour can negatively impact psychological wellbeing. One behavioural addiction that has been increasingly studied empirically is that of Internet Addiction (IA).
Griffiths, MD, Patrão, IM, Pontes, HM
core  

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy