Results 61 to 70 of about 294,548 (281)

Behavioral Symptomatology in the Premenstruum

, 2022
Objective: Sleep and eating behaviors are disturbed during the premenstrual phase of the menstrual cycle in a significant number of reproductive-age women.
Dang, Nhan, Nhan Dang, Soumare, Fatimata, Nusslock, Robin, Fatimata Soumare, Khalil, Dina, Sun, Jiehuan, Aamina Naveed, Dina Khalil, Robin Nusslock, Hamidovic, Ajna, Ajna Hamidovic, Naveed, Aamina, Jiehuan Sun   +13 more
core   +1 more source

Behavioral Profiling in Early Adolescence and Early Adulthood of Male Wistar Rats After Short and Prolonged Maternal Separation [PDF]

, 2020
Early-life stress and its possible correlations to genes, environment, and later health outcomes can only be studied retrospectively in humans. Animal models enable the exploration of such connections with prospective, well-controlled study designs ...
Roman, Erika,, Roman, Erika, Nylander, Ingrid, Lundberg, Stina,, Nylander, Ingrid,, Lundberg, Stina   +5 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Zebrafish sleep displays distinct sub-states

iScience
Summary: Sleep is an essential and evolutionarily conserved behavior. While mammals and several other species have been shown to exhibit well-defined sleep sub-states, it remains unclear to what extent such differentiation exists across the animal ...
Richa Tripathi, Grigorios Oikonomou, Olivia Eliopoulos, David A. Prober, Geoffrey J. Goodhill   +4 more
doaj   +1 more source

Antidepressant Effects of (S)-Ketamine through a Reduction of Hyperpolarization-Activated Current Ih

iScience, 2020
Summary: Compelling evidence suggests that a single sub-anesthetic dose of (R,S)-ketamine exerts rapid and robust antidepressant effects. However, the cellular mechanisms underlying the antidepressant effects of (R,S)-ketamine remain unclear.
Chung Sub Kim, Daniel Johnston
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Preliminary behavioral assessment of cagemates living with conspecifics submitted to chronic restraint stress in mice

, 2017
The capacity of rodents to recognize and respond to emotional signs from a conspecific is a valuable adaptive behavior, which provides essential skills for species survival.
Carneiro de Oliveira, P. E., Carmona, Isabela M., Fonseca, Aura R., Aura R. Fonseca, Azair Canto-de-Souza, Zaniboni, Caroline R., Canto-de-Souza, Azair, Caroline R. Zaniboni, Isabela M. Carmona, Fonseca, Aura R. [UNESP], P.E. Carneiro de Oliveira, Canto-de-Souza, Azair [UNESP]   +11 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

How neuroscience and behavioral genetics improve psychiatric assessment: report on a violent murder case

, 2010
Despite the advances in the understanding of neural and genetic foundations of violence, the investigation of the biological bases of a mental disorder is rarely included in psychiatric evaluation of mental insanity.
PIETRINI, PIETRO, FERRARA SD, PELLEGRINI, SILVIA, RIGONI D, MARIOTTI, VERONICA, COZZA A, MECHELLI A, SARTORI G., MARIOTTI V   +8 more
core   +2 more sources

Task-specific oscillatory synchronization of prefrontal cortex, nucleus reuniens, and hippocampus during working memory

iScience, 2023
Summary: Working memory requires maintenance of and executive control over task-relevant information on a timescale of seconds. Spatial working memory depends on interactions between hippocampus, for the representation of space, and prefrontal cortex ...
Johanne Gertrude de Mooij-van Malsen, Niels Röhrdanz, Anna-Sophia Buschhoff, Thomas Schiffelholz, Torfi Sigurdsson, Peer Wulff   +5 more
doaj   +1 more source