Results 71 to 80 of about 1,452,252 (272)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Mapping the emotional homunculus with fMRI
iScienceSummary: Emotions are commonly associated with bodily sensations, e.g., boiling with anger when overwhelmed with rage. Studies have shown that emotions are related to specific body parts, suggesting that somatotopically organized cortical regions that ...
Michelle Giraud +5 more
doaj +1 more source
Lessons, insights and newly developed tools emerging from behavioral phenotyping core facilities
, 2020 Scientific investigations, in general, and research in neuroscience, in particular, are becoming ever more complex and require the integration of different techniques.
Roman, Erika, +7 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
Behavior matters for neuroscience and neuroscience matters for behavior
Neuroscience & Biobehavioral Reviews, 2023 Vanderschuren, Louk J M J +2 more
openaire +4 more sources
Cross-talk in economics and neuroscience [PDF]
Neuroeconomics is a recent extension of behavioral economics which aims at uncovering the brain mechanisms and activities that mediate regular and anomalous behaviour. Gul and Pesendorfer (2005) have launched a critique against the neuroeconomic research
Sacha Bourgeois-Gironde, Carl Schoonover
core
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Cerebellar α1D- adrenergic receptors mediate stress-induced dystonia in totteringtg/tg mice
Cellular and Molecular Life SciencesEpisodic ataxia type 2 (EA2) is an inherited neurological disorder, where patients suffer from chronic ataxia and severe episodes of motor dysfunction exhibited as dystonia.
Pauline Bohne +6 more
doaj +1 more source
The history of neuroscience in autobiography /
, 1996 This book is the second volume of autobiographical essays by distinguished senior neuroscientists; it is part of the first collection of neuroscience writing that is primarily autobiographical.
Society for Neuroscience. +1 more
core
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source