Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Privacy Enhanced Demand Response with Reputation-based Incentive Distribution [PDF]
Demand response (DR) is a Smart Grid application that aims at managing consumption of electricity in response to supply-side signals. The exchange of sensitive information (i.e., electricity consumption data) between the consumers and the DR provider is ...
Liassas, Georgios +3 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Effects of Media Coverage on Demand [PDF]
Food safety crises usually receive widespread publicity and an extensive media coverage which evidently is mainly negative. Based on previous research, the purpose of this article is to illustrate the impact of positive and negative food safety ...
Dierks, Leef H.
core
Mohammed Khaled Al-Hanawi,1 Martin Limbikani Mwale,2 Tony Mwenda Kamninga3 1Department of Health Services and Hospital Administration, Faculty of Economics and Administration, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Economics ...
Al-Hanawi MK, Mwale ML, Kamninga TM
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Estimating Asymmetric Advertising Response: An Application to U.S. Nonalcoholic Beverage Demand [PDF]
We propose a regime-switching model that allows demand to respond asymmetrically to upward and downward advertising changes. With the introduction of a smooth transition function, the model features smooth rather than abrupt parameter changes between ...
Kaiser, Harry M., Zheng, Yuqing
core
Body Weight as a Motivating Operation: The Effect of Body Weight on Demand for Food in Hens. [PDF]
Demand for wheat and puffed wheat was examined in six hens, using an ascending geometric progression of fixed-ratio schedules of reinforcement. Hens responded by pecking a key for 2-s access to food in 40-min sessions.
Andrews, Tegan Emily Anne-Marie
core
A macro-econometric diagnosis of the Keynesian propositions of the money demand function in Malawi: An error-correction approach [PDF]
The institution of sound monetary policies largely depends on a good understanding of the money demand function. While there have been studies to understand the behaviour of the money demand function in general, critical analyses solely devoted to ...
Ken Chamuva Shawa
doaj
From Demand Stability to Environmental Responsibility: How Ordered Backlogs Shape Firm Behaviour
ABSTRACT Ordered backlogs are the confirmed and yet to be delivered customer orders, which may have multiple advantages to firms. We investigate how ordered backlogs influence firms' future environmental misconduct. Drawing on organisational slack theory, we argue that ordered backlogs as a form of demand‐side slack can reduce ...
Ashutosh Singh +4 more
openaire +1 more source

