Results 111 to 120 of about 8,902,600 (289)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The growth of penetration of wind sources in the power system along with demand response programmes (DRPs) has led the electricity market and decision‐making process in a complicated pathway.
Reza Naghizadeh Kouchesfahani +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The effect of altering maintenance diet on demand for reinforcers. [PDF]
Six hens’ preferences between whole grain wheat, commercial laying pellets and puffed wheat were assessed using a free-access procedure. Wheat was found to be the preferred food of three hens, pellets were preferred by one, puffed wheat was found to be ...
Jackson, Surrey Merryn Kate
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
A demand response approach locally implementable for waterbeds
This paper presents a demand response scheme for waterbeds that can be implemented with currently available infrastructure. It balances the requirements of saving energy and shifting power to times with higher power availability by scheduling heating ...
Turau, Volker, Venzke, Marcus
core +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
A Survey-Assisted Time-Domain Characterization of the Power Patterns of Main Household Appliances
The characterisation of power curves for individual household appliances needs to consider technical and user behaviour-based aspects. To assess the impact of an aggregation of appliances, the combination of non-synchronised power curves of multiple ...
Gianfranco Chicco +3 more
doaj +1 more source

