Results 221 to 230 of about 11,954 (253)

Inducible brown/beige adipocytes in retro-orbital adipose tissues

Experimental Eye Research, 2019
Beige adipocytes and brown adipocytes can generate heat by using mitochondrial uncoupling protein 1 (Ucp1), a thermogenic protein. Browning/beiging is the emergence of beige adipocytes in white adipose tissues (WAT) for cold acclimatization. Here we show the existence of brown/beige adipocytes in retro-orbital WAT in mice. Histologically, Ucp1-positive
Makoto, Sugiyama, Daichi, Shindo, Norihisa, Kanada, Takahiro, Ohzeki, Kazuki, Yoshioka, Masayuki, Funaba, Osamu, Hashimoto   +6 more
openaire   +2 more sources

Concomitant beige adipocyte differentiation upon induction of mesenchymal stem cells into brown adipocytes

Biochemical and Biophysical Research Communications, 2016
The accumulation of fat, which results in obesity, is related to many metabolic disorders. Besides white and brown adipose tissue, beige adipose tissue has recently been recognized as a new type of accumulated fat. Mesenchymal stem cells (MSCs) have been shown to differentiate into brown adipocytes.
Yung-Li, Wang, Shih-Pei, Lin, Patrick C H, Hsieh, Shih-Chieh, Hung   +3 more
openaire   +2 more sources

BDE-99 stimulates generation of aberrant brown/beige adipocytes

Environmental Pollution
Adipose tissue compromises one of the principal depots where brominated flame retardants (BFR) accumulate in vivo, yet whether BFR disturb thermogenic brown/beige adipocytes is still not referred to date. Herein, effects of BDE-99, a major congener of polybrominated diphenyl ethers (PBDEs) detected in humans, on brown/beige adipocytes were explored for
Qing Wen, Xinni Xie, Qidong Ren, Ruiying Pan, Yuguo Du   +4 more
openaire   +2 more sources

Obesity: Beige adipocytes-will they beat obesity?

Nature reviews. Endocrinology, 2016
The mechanistic link between the FTO locus and risk of obesity has remained elusive. However, a new study presents compelling evidence suggesting that the browning of white adipocytes into beige adipocytes (together with regulation of thermogenesis), might be an important and potentially modifiable pathway for development of obesity therapeutics.
Sandholt, Camilla H., Pedersen, Oluf.
openaire   +2 more sources

A mitochondrial trigger for beige adipocyte development

Nature Reviews Endocrinology, 2022
openaire   +2 more sources

Chrna2-driven CRE Is Expressed in Beige Adipocytes

Endocrinology
Abstract Significant research interest has been focused on beige adipocytes, the activation of which improves glucose and lipid homeostasis, therefore representing new therapeutic opportunities for metabolic diseases. Various Cre/Lox-based strategies have been used to investigate the developmental history of beige adipocytes and how ...
Kezhou Zhu, Shanshan Liu, Yunying Huang, Biyang Zhang, Nadia Houssein, Jun Wu   +5 more
openaire   +2 more sources

Beige adipocyte：a novel adipocyte

Academic Journal of Second Military Medical University, 2014
Kai WANG, An-jing REN, Wei-ping ZHANG
openaire   +1 more source

Exploring the Multifaceted Life of Beige Adipocytes

A thesis presented to the faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of ...
openaire   +1 more source

Beige adipocytes—will they beat obesity?

Nature Reviews Endocrinology, 2015
Camilla H. Sandholt, Oluf Pedersen
openaire   +1 more source

White adipocyte dysfunction and obesity-associated pathologies in humans

Nature Reviews Molecular Cell Biology, 2023
Kirsty L Spalding
exaly