Results 61 to 70 of about 11,885 (195)

Pre- and postnatal adipose tissue development in farm animals: from stem cells to adipocyte physiology [PDF]

, 2016
To view supplementary material for this article, please visit http://dx.doi.org/10.1017/S1751731116000872Both white and brown adipose tissues are recognized to be differently involved in energy metabolism and are also able to secrete a variety of ...
Bonnet, Muriel, Gondret, Florence, Louveau, Isabelle, Perruchot, Marie-Hélène   +3 more
core   +3 more sources

Maintaining mitochondria in beige adipose tissue

Adipocyte, 2019
Individual cell types vary enormously in the amount of different organelles they contain. One such organelle is the mitochondrion. Understanding how mitochondrial levels are controlled is essential since so many disease states seem to involve ...
Xiaodan Lu
doaj   +1 more source

Extracellular vesicles from adipose tissue - a potential role in obesity and type 2 diabetes? [PDF]

, 2017
Adipose tissue plays a key role in the development of insulin resistance and its pathological sequelae such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the adipose tissue response to storing excess fatty acids as triglyceride
Freeman, Dilys J., Gao, Xuan, Salomon, Carlos   +2 more
core   +1 more source

Functional Implications of DNA Methylation in Adipose Biology. [PDF]

, 2019
The twin epidemics of obesity and type 2 diabetes (T2D) are a serious health, social, and economic issue. The dysregulation of adipose tissue biology is central to the development of these two metabolic disorders, as adipose tissue plays a pivotal role ...
Kang, Sona, Ma, Xiang
core  

Single cell analysis reveals immune cell-adipocyte crosstalk regulating the transcription of thermogenic adipocytes. [PDF]

, 2019
Immune cells are vital constituents of the adipose microenvironment that influence both local and systemic lipid metabolism. Mice lacking IL10 have enhanced thermogenesis, but the roles of specific cell types in the metabolic response to IL10 remain to ...
Ahn, In Sook, Arneson, Douglas, Diamante, Graciel, Feng, An-Chieh, Hart, Sydney K, Lee, Stephen D, Rajbhandari, Abha K, Rajbhandari, Prashant, Reue, Karen, Santos, Luis C, Smale, Stephen T, Thomas, Brandon J, Tontonoz, Peter, Vergnes, Laurent, Yang, Xia, Zaghari, Nima   +15 more
core   +1 more source

Low temperature exposure induces browning of bone marrow stem cell derived adipocytes in vitro [PDF]

, 2018
Brown and beige adipocytes are characterised as expressing the unique mitochondrial uncoupling protein (UCP)1 for which the primary stimulus in vivo is cold exposure.
A Bartelt, A Krings, A Mostyn, A Mostyn, A Park, A Suzuki, AC Bianco, AG Little, AI Caplan, AM Cypess, AS Borowiec, B Cannon, B Vagaska, C Pontikoglou, C Vogel, CA Schneider, CJ Villanueva, CN Miller, D Patsouris, D Vargas, DL Drehmer, E Lee, EC Cottrell, ID Bloor, J Himms-Hagen, J Ishibashi, J Wu, JM Gimble, JM Jong de, JN Smith, JS Flier, KA Virtanen, L Attig, L Guasti, L Ye, LA Jesus de, LJ Bukowiecki, LS Sidossis, LZ Sharp, M Klingenspor, M Maffei, M Rosenwald, ME Symonds, MP Mollica, N Ghilardi, N Petrovic, P Laharrague, P Puigserver, P Puigserver, R Cancello, RA Garcia, S Cinti, S Cinti, S Dessolin, S Ussar, SM Al-Shibli, V Rizzatti, W Wang, WD Marken Lichtenbelt van, XX Yu, Z Zhou   +60 more
core   +3 more sources

Alternative isoform expression of key thermogenic genes in human beige adipocytes

Frontiers in Endocrinology
BackgroundThe beneficial effect of thermogenic adipocytes in maintaining body weight and protecting against metabolic disorders has raised interest in understanding the regulatory mechanisms defining white and beige adipocyte identity.
Sarah Hazell Pickering, Mohamed Abdelhalim, Philippe Collas, Philippe Collas, Nolwenn Briand   +4 more
doaj   +1 more source

Adipocyte browning and higher mitochondrial function in peri-adrenal but not subcutaneous fat in pheochromocytoma [PDF]

, 2016
Context: Patients with pheochromocytoma (pheo) show presence of multilocular adipocytes that express uncoupling protein (UCP) 1 within periadrenal (pADR) and omental (OME) fat depots. It has been hypothesized that this is due to adrenergic stimulation
Avital Harari, Betz, Bordicchia, Cannon, Chondronikola, Cypess, Cypess, Cypess, de Jong, Di Franco, Frontini, Giordano, Graeme R. Davies, Harold S. Sacks, Himms-Hagen, Hondares, Huang, Jason Y. Lin, Jespersen, Kajimura, Karen Reue, Kern, Laurent Vergnes, Leibel, Lidell, Masha J. Livhits, Michael E. Symonds, Michael W. Yeh, Nagano, Nedergaard, Patsouris, Petrovic, Plouin, Rogers, Sacks, Seale, Sharp, Shinoda, Sidossis, Stepniakowski, Strack, Svensson, Søndergaard, Ussar, van der Lans, van Marken Lichtenbelt, Virtanen, Waldén, Wu   +48 more
core   +1 more source

γ-synuclein is a novel player in the control of body lipid metabolism [PDF]

, 2013
Peer reviewedPublisher ...
Buchman, Vladimir L, Millership, Steven, Ninkina, Natalia, Rochford, Justin J   +3 more
core   +1 more source

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

eLife
The energy-burning capability of beige adipose tissue is a potential therapeutic tool for reducing obesity and metabolic disease, but this capacity is decreased by aging. Here, we evaluate the impact of aging on the profile and activity of adipocyte stem
Corey D Holman, Alexander P Sakers, Ryan P Calhoun, Lan Cheng, Ethan C Fein, Christopher Jacobs, Linus Tsai, Evan D Rosen, Patrick Seale   +8 more
doaj   +1 more source