Results 171 to 180 of about 38,129 (248)
PROTEOMICS, Volume 25, Issue 19, Page 12-25, October 2025.ABSTRACT The ascidian Boytryllus schlosseri is a marine chordate that thrives under conditions of anthropogenic climate change. The B. schlosseri expressed proteome contains unusually high levels of proteins adducted with 4‐hydroxy‐2‐nonenal (HNE). HNE represents a prominent posttranslational modification resulting from oxidative stress.
Dietmar Kültz +6 more
wiley +1 more source
Aging Cell, Volume 24, Issue 10, October 2025.Restriction of dietary BCAAs protects male mice from the metabolic consequences of both normal‐ and high‐protein diets. BCAA restriction also protects from hepatic cellular senescence in vivo and in vitro, especially in the context of mitochondrial stress. ABSTRACT Dietary protein is a key regulator of healthy aging in both mice and humans.
Mariah F. Calubag +14 more
wiley +1 more source
PLoS ONE, 2019 With rapid economic development, the prevalence of obesity has increased remarkably worldwide. Obesity can induce a variety of metabolic diseases, such as atherosclerosis, diabetes, hypertension and coronary heart disease, which significantly endanger ...
Haoyu Li +7 more
doaj +1 more source
Eosinophils and Type 2 Cytokine Signaling in Macrophages Support the Biogenesis of Cold-induced Beige Fat [PDF]
, 2016 YunJae Jung
openalex +1 more source
Perirenal Fat in Disease Progression: From Inflammatory Mediator to Therapeutic Target
International Journal of Urology, Volume 32, Issue 10, Page 1314-1320, October 2025.ABSTRACT Perirenal fat (PRF), the adipose tissue that encases the kidneys, has long been considered a passive energy reservoir and mechanical buffer. However, emerging evidence has identified PRF as a biologically active visceral fat depot that secretes adipocytokines, inflammatory mediators, and other bioactive molecules, and thereby contributes to ...
Eiji Kashiwagi
wiley +1 more source
The Roles and Clinical Significance of Major Hepatic‐Derived Metabolites in Hepatocellular Carcinoma
Journal of Gastroenterology and Hepatology, Volume 40, Issue 10, Page 2435-2448, October 2025.ABSTRACT Hepatocellular carcinoma (HCC) is increasingly recognized as a metabolically orchestrated malignancy, in which hepatic‐derived metabolites function not only as byproducts of liver physiology but also as active modulators of tumor biology.
Rui Sun +5 more
wiley +1 more source
Systems biology reveals uncoupling beyond UCP1 in human white fat-derived beige adipocytes [PDF]
, 2017 Elin Nyman +7 more
openalex +1 more source
The Journal of Physiology, Volume 603, Issue 19, Page 5273-5297, October 1, 2025.Abstract figure legend Fibro/adipogenic progenitors (FAPs) are cells resident in the muscle (skeletal and cardiac) niche. FAPs are active participants in the process of muscle degeneration in cardiovascular and neuromuscular diseases. Here, the accumulation of fatty and fibrous tissue is a hallmark.
Elisa Villalobos +2 more
wiley +1 more source
Low expression of brown and beige fat genes in subcutaneous tissues in obese patients [PDF]
, 2018 Aishah Alamrani +3 more
openalex +1 more source