Results 111 to 120 of about 72,325 (270)

Effects of the feeding system on performance and myopathy occurrence in two broiler chicken genotypes [PDF]

open access: yes, 2017
To evaluate whether performance and myopathy occurrence differed according to genotype (Cobb 500 vs. Ross 308) and feeding system (AL: ad libitum vs. ER: early restricted from 13 to 23 d of age, vs.
Birolo, M.   +6 more
core  

No association of CTLA-4 polymorphisms with susceptibility to Behcet disease [PDF]

open access: yes, 2009
Background: Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is a key negative regulator of T lymphocytes and has been shown to be associated with a number of autoimmune diseases. The present study was performed to assess the association between CTLA-
Du, L.   +4 more
core   +2 more sources

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

open access: yesAdvanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li   +12 more
wiley   +1 more source

Sparse whole-genome sequencing identifies two loci for major depressive disorder. [PDF]

open access: yes, 2015
Major depressive disorder (MDD), one of the most frequently encountered forms of mental illness and a leading cause of disability worldwide, poses a major challenge to genetic analysis.
CONVERGE consortium
core   +1 more source

Biomarker Detection in Association Studies: Modeling SNPs Simultaneously via Logistic ANOVA [PDF]

open access: yes, 2014
In genome-wide association studies, the primary task is to detect biomarkers in the form of Single Nucleotide Polymorphisms (SNPs) that have nontrivial associations with a disease phenotype and some other important clinical/environmental factors. However,
Hu, Jianhua   +2 more
core   +2 more sources

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

open access: yesAdvanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi   +18 more
wiley   +1 more source

Association of Single-Nucleotide Polymorphisms in the VDR Gene with Tuberculosis and Infection of Beijing Genotype Mycobacterium tuberculosis. [PDF]

open access: yesInfect Drug Resist, 2023
Yu J   +14 more
europepmc   +1 more source

First description of Mycobacterium tuberculosis Beijing genotype in Argentina.

open access: yesRevista Argentina de microbiologia, 2005
During a population-based study to genotype isolates of Mycobacterium tuberculosis from Buenos Aires Northern suburbs, we found isolates with molecular patterns related to those of the Beijing genotype. Five out of 590 (0.85%) patients had isolates with spoligopattern identical to that of the Beijing family. Since two of these isolates showed identical
Morcillo, N   +9 more
openaire   +2 more sources

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

open access: yesAdvanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang   +18 more
wiley   +1 more source

Comparison of Mycobacterium tuberculosis Beijing genotype with other Mycobacterium tuberculosis strains Using MIRU-VNTR method

open access: yesIranian South Medical Journal, 2012
Background: Recently it is shown that Mycobacterium tuberculosis Beijing genotype are associated with drug resistance. Thus a simple and rapid method is required for identification and differentiation of Beijing family isolates. Therefore the aim of this
Mohaddese Mozafari   +6 more
doaj  

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