Notes: Their molecular characteristics—such as IDH genotype, P53 phenotype, and Ki‐67 labeling index—are critical determinants of treatment strategies and prognosis for patients of adult‐type diffuse gliomas. In this study, we employed 7‐tesla sodium magnetic resonance imaging (23Na MRI) and demonstrated that total sodium concentration (TSC) and ...
Letian Yuan +9 more
wiley +1 more source
The ChickenGTEx portal: a pan-tissue catalogue of regulatory variants shaping transcriptomic and phenotypic diversity. [PDF]
Hou Y +19 more
europepmc +1 more source
The role of 3 mitochondrial complex I gene in host expansion of Bactrocera tau was verified by CRISPR/Cas9 gene editing system. A stable homogenous strain (Btndufa7‐/‐) of B.tau was established after silencing Ndufa7. The reduced size of larvae and pupae of Ndufa7 knockout strain was first found.Then different levels of fitness and relative expression ...
Wei Shi +3 more
wiley +1 more source
Epidemiology and genetic diversity of norovirus GII genogroups among pediatric patients in Beijing, China, during 2023-2024. [PDF]
Ai J +7 more
europepmc +1 more source
Maltase 1 regulates DENV2 infection and life history in Aedes aegypti
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li +5 more
wiley +1 more source
The hidden threats posed by Japanese encephalitis virus genotype V. [PDF]
Li Q, Mishra H, Kain KC, Wang R.
europepmc +1 more source
Glymphatic system dysfunction mediates amyloid deposition and cognitive impairment in Alzheimer's disease: a PET/MRI multimodality imaging study. [PDF]
Xue H +10 more
europepmc +1 more source
A Deep Autoencoder Compression-Based Genomic Prediction Method for Whole-Genome Sequencing Data. [PDF]
Song H +6 more
europepmc +1 more source
Identification of major loci governing 13 agronomic traits and the fine-mapping of CaSUN29 regulating fruit length in pepper. [PDF]
Wang Y +7 more
europepmc +1 more source
AB-QTL analysis in winter wheat: II. Genetic analysis of seedling and field resistance against leaf rust in a wheat advanced backcross population [PDF]
Kunert, A. +4 more
core +1 more source

