Mycobacterium tuberculosis lineage: a naming of the parts [PDF]
There have been many reports of groups of related Mycobacterium tuberculosis strains described variously as lineages, families or clades. There is no objective definition of these groupings making it impossible to define relationships between those ...
Bellamy +25 more
core +1 more source
Imported extensively drug-resistant Mycobacterium tuberculosis Beijing genotype, Marseilles, France, 2011 [PDF]
Multidrug- (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) are reported to gradually spread across European countries with low TB prevalence including France. Some isolates may even accumulate traits of resistance in addition to the XDR profile, as a result of therapeutic mismanagement. We report here the first case of XDR TB in Marseilles
S, Cohen-Bacrie +6 more
openaire +2 more sources
Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population [PDF]
Increasing amounts of evidence has demonstrated that T2DM (Type 2 Diabetes Mellitus) patients have increased susceptibility to CRC (colorectal cancer).
Feng, Jue-Ping +11 more
core +3 more sources
Public health advocacy for the Berlin Declaration on tuberculosis in the former Soviet Union: the view of Médecins Sans Frontières [PDF]
To assist international efforts to address major gaps in the availability and accessibility of quality diagnosis and treatment for multi-drug resistant tuberculosis, Médecins Sans Frontières has adapted an approach combining three sets of interlinked ...
Balabanova D. +6 more
core +2 more sources
Innate Immune Response to Mycobacterium tuberculosis Beijing and Other Genotypes
As a species, Mycobacterium tuberculosis is more diverse than previously thought. In particular, the Beijing family of M. tuberculosis strains is spreading and evaluating throughout the world and this is giving rise to public health concerns. Genetic diversity within this family has recently been delineated further and a specific genotype, called ...
Wang, C +7 more
openaire +7 more sources
Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan Africa [PDF]
Tuberculosis (TB) remains a global emergency and is responsible for 1.7 million deaths annually. Widespread global misuse of isoniazid and rifampicin over three decades has resulted in emergence of the ominous spread of multidrug-resistant TB (MDR-TB ...
Abdool Karim +70 more
core +1 more source
Mutations in mutT genes of Mycobacterium tuberculosis isolates of Beijing genotype [PDF]
Missense alterations in genes mutT4 and mutT2, which encode DNA repair enzymes, were sequenced from 30 clinical isolates of Mycobacterium tuberculosis of Beijing genotype, mostly from patients with primary tuberculosis, to evaluate their contribution to anti-mycobacterial drug resistance.
GARZELLI, CARLO +4 more
openaire +2 more sources
In vivo virulence of Beijing genotype Mycobacterium tuberculosis
Mycobacterium tuberculosis Beijing genotype strains comprise 5080% in Russian Federation, which are divided into the main B0/W148, CladeA, and CAO clusters based on VNTR and SNP analysis. It should be noted that such phylogenetically highly close MTB strains belong to the modern Beijing family, generally demonstrating high transmissibility, association
J. A. Bespyatykh +9 more
openaire +3 more sources
Investigation on Mycobacterium tuberculosis diversity in China and the origin of the Beijing clade.
BackgroundInvestigation of the genetic diversity of Mycobacterium tuberculosis in China has shown that Beijing genotype strains play a dominant role in the tuberculosis (TB) epidemic.
Kanglin Wan +13 more
doaj +1 more source
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source

