Results 41 to 50 of about 72,325 (270)

Mycobacterium tuberculosis lineage: a naming of the parts [PDF]

open access: yes, 2005
There have been many reports of groups of related Mycobacterium tuberculosis strains described variously as lineages, families or clades. There is no objective definition of these groupings making it impossible to define relationships between those ...
Bellamy   +25 more
core   +1 more source

Imported extensively drug-resistant Mycobacterium tuberculosis Beijing genotype, Marseilles, France, 2011 [PDF]

open access: yesEurosurveillance, 2011
Multidrug- (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) are reported to gradually spread across European countries with low TB prevalence including France. Some isolates may even accumulate traits of resistance in addition to the XDR profile, as a result of therapeutic mismanagement. We report here the first case of XDR TB in Marseilles
S, Cohen-Bacrie   +6 more
openaire   +2 more sources

Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population [PDF]

open access: yes, 2016
Increasing amounts of evidence has demonstrated that T2DM (Type 2 Diabetes Mellitus) patients have increased susceptibility to CRC (colorectal cancer).
Feng, Jue-Ping   +11 more
core   +3 more sources

Public health advocacy for the Berlin Declaration on tuberculosis in the former Soviet Union: the view of Médecins Sans Frontières [PDF]

open access: yes, 2012
To assist international efforts to address major gaps in the availability and accessibility of quality diagnosis and treatment for multi-drug resistant tuberculosis, Médecins Sans Frontières has adapted an approach combining three sets of interlinked ...
Balabanova D.   +6 more
core   +2 more sources

Innate Immune Response to Mycobacterium tuberculosis Beijing and Other Genotypes

open access: yesPLoS ONE, 2010
As a species, Mycobacterium tuberculosis is more diverse than previously thought. In particular, the Beijing family of M. tuberculosis strains is spreading and evaluating throughout the world and this is giving rise to public health concerns. Genetic diversity within this family has recently been delineated further and a specific genotype, called ...
Wang, C   +7 more
openaire   +7 more sources

Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan Africa [PDF]

open access: yes, 2010
Tuberculosis (TB) remains a global emergency and is responsible for 1.7 million deaths annually. Widespread global misuse of isoniazid and rifampicin over three decades has resulted in emergence of the ominous spread of multidrug-resistant TB (MDR-TB ...
Abdool Karim   +70 more
core   +1 more source

Mutations in mutT genes of Mycobacterium tuberculosis isolates of Beijing genotype [PDF]

open access: yesJournal of Medical Microbiology, 2006
Missense alterations in genes mutT4 and mutT2, which encode DNA repair enzymes, were sequenced from 30 clinical isolates of Mycobacterium tuberculosis of Beijing genotype, mostly from patients with primary tuberculosis, to evaluate their contribution to anti-mycobacterial drug resistance.
GARZELLI, CARLO   +4 more
openaire   +2 more sources

In vivo virulence of Beijing genotype Mycobacterium tuberculosis

open access: yesRussian Journal of Infection and Immunity, 2019
Mycobacterium tuberculosis Beijing genotype strains comprise 5080% in Russian Federation, which are divided into the main B0/W148, CladeA, and CAO clusters based on VNTR and SNP analysis. It should be noted that such phylogenetically highly close MTB strains belong to the modern Beijing family, generally demonstrating high transmissibility, association
J. A. Bespyatykh   +9 more
openaire   +3 more sources

Investigation on Mycobacterium tuberculosis diversity in China and the origin of the Beijing clade.

open access: yesPLoS ONE, 2011
BackgroundInvestigation of the genetic diversity of Mycobacterium tuberculosis in China has shown that Beijing genotype strains play a dominant role in the tuberculosis (TB) epidemic.
Kanglin Wan   +13 more
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

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