Results 61 to 70 of about 72,325 (270)
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease [PDF]
, 2015 Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association studies (GWAS) analysis of common SNPs.Alver, Maris, Anand, Sonia S., Ardissino, Diego, Armasu, Sebastian M., Assimes, Themistocles L., Auro, Kirsi, Bertram, Lars, Beutner, Frank, Bjonnes, Andrew, Boerwinkle, Eric, Borecki, Ingrid B., Bottinger, Erwin P., Buring, Julie E., Chambers, John C., Chasman, Daniel I., Chen, Shufeng, Clarke, Robert, Collins, Rory, Cupples, L. Adrienne, Danesh, John, de Andrade, Mariza, de Vries, Paul S., Dedoussis, George, Dehghan, Abbas, Deloukas, Panos, Demuth, Ilja, Elosua, Roberto, Epstein, Stephen E., Erdmann, Jeanette, Esko, Tonu, Farrall, Martin, Feitosa, Mary F., Ford, Ian, Franceschini, Nora, Franco, Oscar H., Franzosi, Maria Grazia, Frossard, Philippe, Gauguier, Dominique, Gieger, Christian, Goel, Anuj, Goodall, Alison H., Gottesman, Omri, Grace, Christopher, Granger, Christopher B., Gu, Dongfeng, Gudnason, Vilmundur, Gustafsson, Stefan, Haber, Marc, Hall, Alistair S., Hall, Leanne M., Hamsten, Anders, Han, Bok-Ghee, Harris, Tamara B., Hazen, Stanley L., Hengstenberg, Christian, Hofman, Albert, Hopewell, Jemma C., Huang, Jianfeng, Huang, Jie, Hwang, Shih-Jen, Ingelsson, Erik, Iribarren, Carlos, Jalilzadeh, Shapour, Jukema, J. Wouter, Kanoni, Stavroula, Karhunen, Pekka J., Kathiresan, Sekar, Kessler, Thorsten, Kim, Bong-Jo, Kim, Yun Kyoung, Kleber, Marcus E., Koenig, Inke R., Kooner, Jaspal S., Kullo, Iftikhar J., Kyriakou, Theodosios, Lannfelt, Lars, Lau, King Wai, Lehtimaki, Terho, Lieb, Wolfgang, Lind, Lars, Lindgren, Cecilia M., Lokki, Marja-Liisa, Loos, Ruth J. F., Lu, Xiangfeng, Lu, Yingchang, Lund University., Lund University., Lund University., Lyytikainen, Leo-Pekka, Maerz, Winfried, Magnusson, Patrik K., Mallick, Nadeem H., McPherson, Ruth, Mehra, Narinder, Meitinger, Thomas, Melander, Olle,, Memon, Fazal-ur-Rehman, Metspalu, Andres, Mihailov, Evelin, Morris, Andrew P., Morrison, Alanna C., Nelson, Christopher P., Nieminen, Markku S., Nikpay, Majid, O'Donnell, Christopher J., Palmer, Colin N., Pedersen, Nancy L., Perola, Markus, Pervjakova, Natalia, Peters, Annette, Qu, Liming, Quertermous, Thomas, Rader, Daniel J., Rallidis, Loukianos S., Rasheed, Asif, Reilly, Muredach P., Ridker, Paul M., Ripatti, Samuli, Roberts, Robert, Rose, Lynda M., Saleheen, Danish, Salfati, Elias, Salomaa, Veikko, Samani, Nilesh J., Samuel, Maria, Sanghera, Dharambir K., Saxena, Richa, Scholz, Markus, Schunkert, Heribert, Schwartz, Stephen M., Seedorf, Udo, Shah, Svati H., Sinisalo, Juha, Smith, Albert V., Stewart, Alexandre F., Stirrups, Kathleen E., Stott, David J., Thiery, Joachim, Thompson, John R., Tikkanen, Emmi, Trompet, Stella, Uitterlinden, Andre, van Zuydam, Natalie R., Wang, Laiyuan, Watkins, Hugh, Webb, Thomas R., Willenborg, Christina, Won, Hong-Hee, Yang, Xueli, Zalloua, Pierre A., Zaman, Khan S., Zeng, Lingyao, Zhang, Weihua, Zhao, Wei +153 morecore +5 more sourcesSNP/RD typing of Mycobacterium tuberculosis Beijing strains reveals local and worldwide disseminated clonal complexes. [PDF]
PLoS ONE, 2011 The Beijing strain is one of the most successful genotypes of Mycobacterium tuberculosis worldwide and appears to be highly homogenous according to existing genotyping methods.Anita C Schürch, Kristin Kremer, Amber C A Hendriks, Benthe Freyee, Christopher R E McEvoy, Reinout van Crevel, Martin J Boeree, Paul van Helden, Robin M Warren, Roland J Siezen, Dick van Soolingen +10 moredoaj +1 more sourceComprehensive Characterization of the Transmitted/Founder env Genes From a Single MSM Cohort in China [PDF]
, 2015 Background: The men having sex with men (MSM) population has become one of the major risk groups for HIV-1 infection in China. However, the epidemiological patterns, function of the env genes, and autologous and heterologous neutralization activity in ...Cai, F, Chen, Y, Gao, F, Huang, X, Jiang, C, Li, N, Meng, Z, Montefiori, DC, Vandergrift, N, Wu, H, Xin, R, Xu, X, Zhang, T, Zhang, X +13 morecore +1 more sourceGenome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes
Advanced Science, EarlyView.This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium +51 morewiley +1 more sourceTuberculosis outcomes related to the Mycobacterium tuberculosis genotype
Инфекция и иммунитет, 2019 Mycobacterium tuberculosis strains of different phylogenetic lineages and genetic families differ in biological properties that determine, to some extent, epidemiological features and clinical manifestation in tuberculosis (TB) patients.The aim of the ...O. A. Pasechnik, A. A. Vyazovaya, M. A. Dymova, A. I. Blokh, V. L. Stasenko, M. P. Tatarintseva, I. V. Mokrousov +6 moredoaj +1 more sourcePopulation structure of mixed Mycobacterium tuberculosis infection is strain genotype and culture medium dependent. [PDF]
PLoS ONE, 2013 BACKGROUND: Molecular genotyping methods have shown infection with more than one Mycobacterium tuberculosis strain genotype in a single sputum culture, indicating mixed infection.Madeleine Hanekom, Elizabeth M Streicher, Doreen Van de Berg, Helen Cox, Cheryl McDermid, Marlein Bosman, Nicolaas C Gey van Pittius, Tommie C Victor, Martin Kidd, Dick van Soolingen, Paul D van Helden, Robin M Warren +11 moredoaj +1 more sourceMettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS
Advanced Science, EarlyView.This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao +14 morewiley +1 more sourceMultidrug-Resistant Tuberculosis in Prison Inmates, Azerbaijan
Emerging Infectious Diseases, 2001 In a tuberculosis (TB) program in the Central Penitentiary Hospital of Azerbaijan, we analyzed 65 isolates of Mycobacterium tuberculosis by IS6110-based restriction fragment-length polymorphism (RFLP) and spoligotyping.Gaby E. Pfyffer, Anni Strässle, Tamara van Gorkum, Françoise Portaels, Leen Rigouts, Christine Mathieu, Fuad Mirzoyev, Hamidou Traore, Jan D.A. van Embden +8 moredoaj +1 more sourceDNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]
, 2010 Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.Adams, Afanasev, Alina E. Gorna, Aly, Arnold, Bacon, Banu, Bergval, Betts, Boshoff, Boshoff, Bostanabad, Burney, Capelli, Chan, Chan, Cheng, Cooper, Cubillos-Ruiz, Darwin, Darwin, Das, Davis, Dos Vultos, Dubnau, Durbach, Farnia, Fennelly, Filliol, Fleischmann, Flint, Fontan, Friedberg, Frischkorn, Fu, Fu, Gaynor, Gordhan, Graham, Grishko, Guthlein, Hampshire, Hazbon, Hughes, Jain, Jaroslaw Dziadek, Jiao, Kapur, Karakousis, Karakousis, Karunkaran, Katti, Kesavan, Kim, Ko, Ko, Korycka-Machala, Krokan, Kurthkoti, Kurthkoti, Lari, Lever, Loudon, MacMicking, Malshetty, Martinez, Mokrousov, Moller, Movahedzadeh, Mulder, Munoz-Elias, Muttucumaru, Nguyen, Niemann, Nikolayevskyy, Nouvel, O'sullivan, Olano, Peccia, Peccia, Pitcher, Rachman, Rachman, Rad, Ramaswamy, Richard P. Bowater, Riley, Saito, Sander, Sassetti, Sassetti, Saunders, Schnappinger, Schwab, Sherman, Sinha, Sinha, Smeulders, Springer, Srivastava, Stephanou, Talaat, Talaat, Tang, Tsai, Venkatesh, Vilcheze, Voskuil, Voskuil, Waddell, Wanner, Warner, Weikert, Wiid, Wiseman, World Health Organization, Zaczek, Zainuddin +117 morecore +1 more source