Results 61 to 70 of about 80,347 (250)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Bounds on Information Combining With Quantum Side Information

open access: yes, 2017
"Bounds on information combining" are entropic inequalities that determine how the information (entropy) of a set of random variables can change when these are combined in certain prescribed ways.
Hirche, Christoph, Reeb, David
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Measuring Uncertainty in the Negation Evidence for Multi-Source Information Fusion

open access: yesEntropy, 2022
Dempster–Shafer evidence theory is widely used in modeling and reasoning uncertain information in real applications. Recently, a new perspective of modeling uncertain information with the negation of evidence was proposed and has attracted a lot of ...
Yongchuan Tang, Yong Chen, Deyun Zhou
doaj   +1 more source

Algebraic varieties with automorphism groups of maximal rank

open access: yes, 2012
We confirm, to some extent, the belief that a projective variety X has the largest number (relative to the dimension of X) of independent commuting automorphisms of positive entropy only when X is birational to a complex torus or a quotient of a torus ...
A. Fujiki   +22 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Hybrid Fuzzy Soft Sets Decision Making Method in Medical Diagnosis

open access: yesIEEE Access, 2018
The existing approaches for fuzzy soft sets decision-making are mainly based on different types of level soft sets. How to deal with such kinds of fuzzy soft sets decision-making problems via decreasing the uncertainty resulting from human's subjective ...
Fuyuan Xiao
doaj   +1 more source

Entanglement in gapless resonating valence bond states

open access: yes, 2013
We study resonating-valence-bond (RVB) states on the square lattice of spins and of dimers, as well as SU(N)-invariant states that interpolate between the two.
Blote H W J   +20 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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