Results 31 to 40 of about 1,796,615 (281)

Experimental study on HSS model parameters for marine soft soils in Yangjiang, Guangdong Province

open access: yesYantu gongcheng xuebao, 2021
The offshore wind turbine structure has strict control criteria of the tilt and the resonant frequency of the foundation, while the small strain stiffness of the marine soils plays an important role in these properties.
GU Xiao-qiang 1, 2, LIU Wen-qian 1, 2, CHEN Xi-yuan 1, 2, LIN Yi-feng 3, XIAO Jian-dong 3, WU Cai-hong 3
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Dissipation boundaries for bender element experiments on geomaterials based on experimental and computational models

open access: yesTransportation Engineering
The bender element (BE) test is widely employed in geotechnical engineering for measuring the shear wave velocity (Vs) and, consequently, the small-strain shear modulus (G0), due to its ease of application, integration into geotechnical devices, and ...
Ionuţ Dragoş Moldovan   +3 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Monitoring lime and cement improvement using spectral induced polarization and bender element techniques

open access: yesJournal of Rock Mechanics and Geotechnical Engineering, 2021
Spectral induced polarization (SIP) and bender element (BE) techniques show a high sensitivity to particle size, particle distribution and content of generated hydration products, which essentially govern the efficiency of ground improvement.
Bate Bate   +4 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Development of PLC-controlled bender element array and its implementation in laterally loaded pile experiments

open access: yesYantu gongcheng xuebao
To enable real-time monitoring and evaluation of the soil stiffness characteristics, a bender element array system suitable for model testing has been developed. The system is based on a PLC control unit and employs a multi-channel switching architecture
HU Anfeng 1, 2, CHEN Yiyang 1, 2, WU Juntao 1, 2, WANG Jinchang 3, XIAO Zhirong 4
doaj   +1 more source

Simulasi Pembebanan Komponen Bender pada Desain Mesin Begel Fabricator Menggunakan Software Autodesk Inventor 2020

open access: yesQuantum Teknika, 2021
Stress analysis of the bender components in the design of the begel fabricator machine was carried out using FEA (Finite Element Analysis) with three variations of the constituent material parameters, namely 6061 aluminum, mild steel, and cast iron with ...
Satriawan Dini Hariyanto   +1 more
doaj   +1 more source

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